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美国西北部地区骨科创伤患者的血清维生素 D 水平。

Serum vitamin D levels in orthopaedic trauma patients living in the northwestern United States.

机构信息

Oregon Health Sciences University, Portland, OR, USA.

出版信息

J Orthop Trauma. 2013 May;27(5):e103-6. doi: 10.1097/BOT.0b013e31825cf8fb.

Abstract

OBJECTIVE

To determine the incidence of vitamin D deficiency in orthopaedic trauma patients undergoing fracture surgery living in the Northwest United States.

DESIGN

Retrospective observational cohort study.

SETTING

Level 2 trauma center.

PATIENTS

Two cohorts of patients undergoing fracture repair surgery during a 3-month period in winter and summer had serum vitamin D levels drawn at the time of surgery. One hundred three patients were reviewed in the winter cohort and 98 in the summer cohort.

MAIN OUTCOME MEASURE

Serum 25(OH) vitamin D levels of patients undergoing fracture repair surgery.

RESULTS

Normal levels of vitamin D were considered to be between 32 and 80 ng/mL. Most patients in both cohorts were vitamin D insufficient. The average level for the winter cohort was 26.4 ng/mL, which was significantly lower than the average level for the summer cohort, 29.8 ng/mL (P = 0.03).

CONCLUSIONS

A high incidence of vitamin D insufficiency and deficiency likely exists across all age groups in orthopaedic trauma patients living in the Northwest United States and regions with similarly northern latitude. Further study is required to confirm improved fracture healing with normalization of serum vitamin D levels.

LEVEL OF EVIDENCE

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

确定居住在美国西北部的行骨折手术的骨科创伤患者中维生素 D 缺乏症的发生率。

设计

回顾性观察性队列研究。

地点

二级创伤中心。

患者

在冬季和夏季的 3 个月期间行骨折修复手术的两个队列的患者在手术时抽取血清维生素 D 水平。对冬季队列中的 103 名患者和夏季队列中的 98 名患者进行了回顾。

主要观察指标

行骨折修复手术患者的血清 25(OH)维生素 D 水平。

结果

维生素 D 的正常水平被认为在 32 和 80ng/ml 之间。两个队列中的大多数患者均存在维生素 D 不足。冬季队列的平均水平为 26.4ng/ml,明显低于夏季队列的平均水平 29.8ng/ml(P = 0.03)。

结论

在美国西北部和类似纬度地区的所有骨科创伤患者中,维生素 D 不足和缺乏的发生率可能很高。需要进一步的研究来证实血清维生素 D 水平正常化可改善骨折愈合。

证据水平

预后 IV 级。请参阅作者说明以获取证据水平的完整描述。

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