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骨科创伤患者维生素D缺乏症的患病率:来自三级创伤中心的横断面调查

Prevalence of Vitamin D Deficiency in Orthopedic Trauma Patients: A Cross-Sectional Survey From a Tertiary Care Trauma Center.

作者信息

Singh Shailendra, Vimal Yuvraj, Srivastava Shubham, Mohan Ravindra, Kumar Deepak, Rastogi Devarshi, Gupta Pranjal, Singh Balwinder, Gupta Anuradha

机构信息

Department of Orthopaedic Surgery, King George's Medical University, Lucknow, IND.

Department of Orthopaedic Surgery, Sarojini Naidu Medical College, Agra, IND.

出版信息

Cureus. 2024 Sep 11;16(9):e69174. doi: 10.7759/cureus.69174. eCollection 2024 Sep.

DOI:10.7759/cureus.69174
PMID:39398769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11468408/
Abstract

Background Vitamin D deficiency is prevalent globally, with potential consequences for bone health and trauma outcomes. This study aimed to assess the prevalence of vitamin D deficiency in orthopedic trauma patients and investigate its correlation with various demographic and injury-related factors. Methodology A cross-sectional investigation was undertaken at a tertiary care center. An evaluation of serum 25-hydroxyvitamin D3 levels was conducted on 124 individuals, aged 20 to 70 years, who were hospitalized with orthopedic injuries. Demographic information, the injury method, the bone involvement pattern, and socioeconomic status were documented. Statistical analysis was employed to evaluate the correlations between vitamin levels D and these variables. Results The overall prevalence of vitamin D deficiency was 54 (43.6%) cases, with nine (7.3%) cases exhibiting severe deficiency and 45 (36.3%) cases exhibiting moderate deficiency. Higher rates of deficiency were associated with lower socioeconomic status (p = 0.044) and low-velocity trauma (p = 0.037). No significant association was found with age, sex, or residence. Interestingly, patients with multiple fractures were more prone to deficiency compared to those with single fractures. Conclusions This survey revealed a significant vitamin D deficiency among orthopedic trauma patients. Factors such as socioeconomic status and the nature of the injury emerged as significant risk factors. While conducting routine vitamin D assessments might pose challenges in developing nations, consistent supplementation could prove advantageous in enhancing fracture healing and overall health outcomes among this demographic. There is a call for future research to delve deeper into the role of vitamin D in trauma management and refine supplementation strategies.

摘要

背景

维生素D缺乏在全球普遍存在,对骨骼健康和创伤预后有潜在影响。本研究旨在评估骨科创伤患者维生素D缺乏的患病率,并调查其与各种人口统计学和损伤相关因素的相关性。

方法

在一家三级护理中心进行了一项横断面调查。对124名年龄在20至70岁之间因骨科损伤住院的患者进行了血清25-羟基维生素D3水平评估。记录了人口统计学信息、损伤方式、骨骼受累模式和社会经济状况。采用统计分析来评估维生素D水平与这些变量之间的相关性。

结果

维生素D缺乏的总体患病率为54例(43.6%),其中9例(7.3%)为严重缺乏,45例(36.3%)为中度缺乏。较高的缺乏率与较低的社会经济地位(p = 0.044)和低速创伤(p = 0.037)相关。未发现与年龄、性别或居住地有显著关联。有趣的是,与单处骨折患者相比,多处骨折患者更容易缺乏维生素D。

结论

这项调查显示骨科创伤患者中存在显著的维生素D缺乏。社会经济地位和损伤性质等因素成为重要的风险因素。虽然在发展中国家进行常规维生素D评估可能具有挑战性,但持续补充维生素D可能有利于促进该人群的骨折愈合和整体健康预后。呼吁未来的研究更深入地探讨维生素D在创伤管理中的作用,并完善补充策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef1/11468408/cbdff0cdd5e7/cureus-0016-00000069174-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef1/11468408/ce16de9ffb91/cureus-0016-00000069174-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef1/11468408/cbdff0cdd5e7/cureus-0016-00000069174-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef1/11468408/ce16de9ffb91/cureus-0016-00000069174-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef1/11468408/cbdff0cdd5e7/cureus-0016-00000069174-i02.jpg

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The role of vitamin D and vitamin D deficiency in orthopaedics and traumatology-a narrative overview of the literature.
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BMJ Open. 2021 Mar 22;11(3):e042227. doi: 10.1136/bmjopen-2020-042227.
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