评估冠状动脉搭桥手术患者术后发热的频率。

Evaluating the frequency of postoperative Fever in patients with coronary artery bypass surgey.

作者信息

Rostami Mojtaba, Mirmohammadsadeghi Mohsen, Zohrenia Hossein

机构信息

Associate Professor, Infectious Diseases Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

ARYA Atheroscler. 2011 Fall;7(3):119-23.

PMID:22577458

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3347853/

Abstract

BACKGROUND

Nowadays, coronary artery bypass graft (CABG) is a frequent surgery in treatment of coronary artery disease. According to high expense of this surgery and its important role in patients' quality of life, high survival rate of patients and success of surgery are necessary. The aim of this study was the evaluation of fever incidence (febrile events) due to incidence of pneumonia, wound infection, bacteremia, urinary tract infection and inflammatory response without infection after CABG.

METHODS

In an intergrades descriptive-analytical study, 107 patients who underwent coronary artery bypass graft (CABG) were enrolled in the study. The patients then were examined by the febrile events and also their characteristics including age, sex, duration of surgery, underlying diseases, and frequency distribution of antibiotics consumptions in pre-surgical and postsurgical periods, and incidence of infectious syndromes.

RESULTS

Frequency distribution of febrile events after CABG was 29.9 percent. The most common administered antibiotic before the surgery was cephalothin (Keflin) and then, cefazolin. The most common administered antibiotic after the surgery was cephalothin (Keflin) and cephalexin (47.7%) and then, cephalothin-gentamicin-cephalexin (31.8%). The average age of patients without febrile syndrome was 60.53 years and in those with febrile syndrome was 59.31 years. In terms of gender, 74.8% of the patients were males. So that 32.5% of males and 22.2% of females had fever. The incidence time of fever in most cases was in the postoperative fourth day. In terms of underlying diseases, 13 percent of them had hypertension and hyperlipidemia, 14 percent had only hypertension, 11.2 percent had only hyperlipidemia and 6.5 percent had diabetes.

CONCLUSION

This study showed that the prevalence of fever in patients undergoing CABG was 29.9 percent and the most common cause of fever was sternal infections. There was a significant correlation between administered antibiotics in preoperative and postoperative periods and febrile syndrome.

摘要

背景

如今，冠状动脉旁路移植术（CABG）是治疗冠状动脉疾病的常见手术。鉴于该手术费用高昂且对患者生活质量、生存率有着重要影响，确保高成功率和患者高生存率至关重要。本研究旨在评估冠状动脉旁路移植术后因肺炎、伤口感染、菌血症、尿路感染及无感染性炎症反应而导致的发热发生率（发热事件）。

方法

在一项等级描述性分析研究中，107例行冠状动脉旁路移植术（CABG）的患者纳入研究。随后对患者进行发热事件检查，并了解其特征，包括年龄、性别、手术时长、基础疾病、术前及术后抗生素使用频率分布以及感染综合征发生率。

结果

冠状动脉旁路移植术后发热事件的发生率为29.9%。术前最常用的抗生素是头孢噻吩（凯福林），其次是头孢唑林。术后最常用的抗生素是头孢噻吩（凯福林）和头孢氨苄（47.7%），其次是头孢噻吩 - 庆大霉素 - 头孢氨苄（31.8%）。无发热综合征患者的平均年龄为60.53岁，有发热综合征患者的平均年龄为59.31岁。在性别方面，74.8%的患者为男性。其中32.5%的男性和22.2%的女性出现发热。多数情况下发热发生在术后第四天。在基础疾病方面，13%的患者患有高血压和高脂血症，14%的患者仅患有高血压，11.2%的患者仅患有高脂血症，6.5%的患者患有糖尿病。