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[利用热扩散血流仪进行局部脑血流监测。3例病例描述]

[Regional cerebral blood flow monitoring using thermal diffusion flowmetry. Description of 3 cases].

作者信息

Pacreu S, Villalba G, Gracia M P, Quijada C, Moltó L, Fernández S

机构信息

Servicio de Anestesiología y Reanimación, Hospital del Mar, Parc de Salut Mar, Barcelona, España.

出版信息

Rev Esp Anestesiol Reanim. 2012 Aug-Sep;59(7):394-7. doi: 10.1016/j.redar.2012.03.016. Epub 2012 May 10.

Abstract

Cerebral blood flow is the most important physiologic parameter in the setting of brain injury. A regional measurement of the flow (rCBF), can be obtained using continuous methods such as thermal diffusion flowmetry (TD-rCBF). This technology of monitoring allows us to detect and quantify ischemic events related with the temporary artery clipping or malposition of the definitive clip and in patients who have suffered a subarachnoid hemorrhage (SAH) or a traumatic brain injury. Likewise, the precocious detection of ischemic events might help us to adopt more rapidly therapeutic measures and more efficienty. Three cases show during aneurysm clipping procedures and at intensive care: the effects of different hypnotics on TD-rCBF values; the relationship between TD-rCBF and somatosensory and motor evoked potentials; and changes in TD-rCBF and transcranial Doppler ultrasonography (TDU) during a vasospasm. TD-rCBF showed in real-time flow variations induced by anaesthetics and detected changes of CBF earlier than evoked potentials and TDU.

摘要

脑血流量是脑损伤情况下最重要的生理参数。可以使用连续方法,如热扩散血流测定法(TD-rCBF)来获得区域血流测量值(rCBF)。这种监测技术使我们能够检测和量化与临时动脉夹闭或永久性夹位置不当相关的缺血事件,以及蛛网膜下腔出血(SAH)或创伤性脑损伤患者的缺血事件。同样,缺血事件的早期检测可能有助于我们更快地采取治疗措施并提高效率。三个病例展示了在动脉瘤夹闭手术期间及重症监护时:不同催眠药对TD-rCBF值的影响;TD-rCBF与体感和运动诱发电位之间的关系;以及血管痉挛期间TD-rCBF和经颅多普勒超声(TDU)的变化。TD-rCBF实时显示了麻醉剂引起的血流变化,并且比诱发电位和TDU更早地检测到脑血流量的变化。

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