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自发性下颌骨再生:儿童下颌骨重建的另一种选择?

Spontaneous mandibular regeneration: another option for mandibular reconstruction in children?

作者信息

Sharma Praveen, Williams Rhodri, Monaghan Andrew

机构信息

Birmingham Dental Hospital, St Chad's Queensway, Birmingham B4 6NN, United Kingdom.

出版信息

Br J Oral Maxillofac Surg. 2013 Jul;51(5):e63-6. doi: 10.1016/j.bjoms.2012.04.255. Epub 2012 May 9.

DOI:10.1016/j.bjoms.2012.04.255
PMID:22578705
Abstract

Treatment for conditions of the mandible may require resection of the affected segment, and this may need reconstruction. There are case reports of spontaneous regeneration of segments of excised mandibles that resulted in reduced or no need for reconstruction, and we present four such cases. The age at presentation ranged from 6 to 12 years. In all cases the periosteum was preserved during resection. All patients showed evidence of spontaneous regeneration, both clinically and radiographically, between 3 and 5 months after resection. The planned delayed reconstruction meant that these patients either did not need any bony reconstruction, or needed less than had originally been anticipated. Such regeneration is mostly reported in children, and is thought to be the result of an intact periosteal layer. In patients having planned mandibular resections, where the periosteum is preserved, some spontaneous regeneration should be anticipated and final reconstruction delayed until this is complete.

摘要

下颌骨疾病的治疗可能需要切除受影响的节段,这可能需要进行重建。有关于切除的下颌骨节段自发再生的病例报告,结果是减少或无需进行重建,我们在此呈现4例此类病例。就诊时的年龄范围为6至12岁。所有病例在切除过程中均保留了骨膜。所有患者在切除后3至5个月期间,临床和影像学上均显示出自发再生的迹象。计划中的延迟重建意味着这些患者要么不需要任何骨重建,要么所需的骨重建比最初预期的要少。这种再生大多在儿童中报道,被认为是骨膜层完整的结果。在计划进行下颌骨切除的患者中,若保留了骨膜,应预期会有一些自发再生,最终重建应推迟至再生完成。

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