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深度 16S rRNA 宏基因组学和定量 PCR 分析早产儿粪便微生物群。

Deep 16S rRNA metagenomics and quantitative PCR analyses of the premature infant fecal microbiota.

机构信息

Department of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Villaviciosa, Spain.

出版信息

Anaerobe. 2012 Jun;18(3):378-80. doi: 10.1016/j.anaerobe.2012.04.013. Epub 2012 May 8.

DOI:10.1016/j.anaerobe.2012.04.013
PMID:22579986
Abstract

Metagenomic studies on the gut microbiota of preterm infants are scarce. We characterized the microbiota of 10 days-old neonates by deep 16S rRNA gene metagenomic analysis and compare the results with those obtained by qPCR. Both techniques lead to similar conclusions, allowing differentiating between preterm and full-term infants.

摘要

关于早产儿肠道微生物组的宏基因组研究还很匮乏。我们通过深度 16S rRNA 基因宏基因组分析来描述 10 天大的新生儿的微生物组，并将结果与 qPCR 获得的结果进行比较。这两种技术得出的结论相似，都可以区分早产儿和足月儿。

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