Department of Cardiology, Baskent University Faculty of Medicine, Adana, Turkey.
Biomarkers. 2012 Aug;17(5):447-54. doi: 10.3109/1354750X.2012.685182. Epub 2012 May 15.
To investigate the relation between parathyroid hormone (PTH) and heart failure with preserved ejection fraction (HF-PEF) in outpatients.
One hundred consecutive patients who had preserved left ventricular (LV) ejection fraction and heart failure (HF) symptoms, were enrolled. Echocardiography, assessing the diastolic functions was performed. Blood samples were collected for intact PTH and brain natriuretic peptide (BNP).
Significant correlations between PTH level and predictors of advanced HF-PEF were found (p < 0.05). PTH level and left atrium diameter were found to be independent predictors of DHF.
Measurement of serum PTH provides complementary information for the diagnosis and prognosis of HF-PEF.
探讨甲状旁腺激素（PTH）与射血分数保留的心力衰竭（HF-PEF）门诊患者之间的关系。
入选 100 例连续左心室（LV）射血分数保留和心力衰竭（HF）症状的患者。行超声心动图检查评估舒张功能。采集血样检测完整 PTH 和脑钠肽（BNP）。
发现 PTH 水平与 HF-PEF 的预测因子呈显著相关（p < 0.05）。PTH 水平和左心房直径是 DHF 的独立预测因子。
血清 PTH 的测量为 HF-PEF 的诊断和预后提供了补充信息。
Zotero 插件