Ghriallais Ríona Ní, Bruzzi Mark
a National University of Ireland, Galway, Mechanical and Biomedical Engineering , University Road, Galway , Ireland.
Comput Methods Biomech Biomed Engin. 2014;17(4):318-33. doi: 10.1080/10255842.2012.683427. Epub 2012 May 16.
Computational simulations using finite element analysis are a tool commonly used to analyse stent designs, deployment geometries and interactions between stent struts and arterial tissue. Such studies require large computational models and efforts are often made to simplify models in order to reduce computational time while maintaining reasonable accuracy. The objective of the study is focused on computational modelling and specifically aims to investigate how different methods of modelling stent-artery interactions can affect the results, computational time taken and computational size of the model. Various different models, each with increasing levels of complexity, are used to simulate this analysis, representing the many assumptions and simplifications used in other similar studies in order to determine what level of simplification will still allow for an accurate representation of stent radial force and resulting stress concentrations on the inner lining of the vessel during self-expanding stent deployment. The main conclusions of the study are that methods used in stent crimping impact on the resulting predicted radial force of the stent; that accurate representation of stent-artery interactions can only be made when modelling the full length of the stent due to the incorporation of end effects; and that modelling self-contact of the stent struts greatly impacts on the resulting stress concentrations within the stent, but that the effect of this on the unloading behaviour and resulting radial force of the stent is negligible.
使用有限元分析的计算模拟是一种常用于分析支架设计、展开几何形状以及支架支柱与动脉组织之间相互作用的工具。此类研究需要大型计算模型，并且通常会努力简化模型以减少计算时间，同时保持合理的准确性。该研究的目标聚焦于计算建模，具体旨在探究不同的支架 - 动脉相互作用建模方法如何影响结果、所需的计算时间以及模型的计算规模。使用了各种不同的模型，每个模型的复杂度都在增加，以模拟此分析，代表其他类似研究中所采用的诸多假设和简化，从而确定何种简化程度仍能在自膨胀支架展开过程中准确呈现支架的径向力以及血管内衬上产生的应力集中。该研究的主要结论是，支架压接中使用的方法会影响支架最终预测的径向力；由于纳入了端部效应，只有在对支架全长进行建模时才能准确呈现支架 - 动脉相互作用；对支架支柱的自接触进行建模会极大地影响支架内产生的应力集中，但这对支架的卸载行为和最终径向力的影响可忽略不计。
