Department of Chemical and Biological Engineering, Missouri University of Science and Technology, Rolla, MO 65409-1230, USA.
J Sep Sci. 2012 Apr;35(8):947-56. doi: 10.1002/jssc.201101030.
Stratified column bed systems whose sections are formed by packing adsorbent particles with a partially fractal structure are proposed and studied. The simulation results clearly show that the breakthrough times and the shape of the breakthrough curves obtained from stratified column beds are significantly larger and sharper than those obtained from conventional columns. The stratified column beds provide, to the designer and user of chromatographic column systems, more degrees of freedom with respect to the number of parameters and variables that could be controlled in the design, construction, and operation of efficient chromatographic adsorption systems. Furthermore, the results suggest that the stratified column beds could provide a higher dynamic adsorptive capacity than conventional columns when it is required to increase the column throughput.
提出并研究了由具有部分分形结构的吸附剂颗粒填充而成的分层柱状床系统。模拟结果清楚地表明，分层柱状床获得的穿透时间和穿透曲线的形状明显大于常规床获得的穿透时间和穿透曲线的形状。对于色谱柱系统的设计者和使用者来说，分层柱状床在设计、构建和运行高效色谱吸附系统时，可以提供更多的自由度，控制更多的参数和变量。此外，研究结果表明，当需要增加柱通量时，分层柱状床可以提供比常规床更高的动态吸附能力。
