Gomba S, Varga E, Mórocz I
Department of Pathology, University Medical School of Debrecen, Hungary.
Kidney Int Suppl. 1990 Nov;30:S16-7.
Basolateral interstitial spaces (BLIS) of the murine macula densa (MD) are dilated in kidneys fixed either by in vivo glutaraldehyde perfusion or snap freezing-freeze substitution, suggesting that macula densa intercellular spaces may be normally dilated in the functioning nephron. BLIS are also dilated in MD with luminal obstruction with "hyaline" cylinder. This finding might indicate a glomerulo-macular fluid and solute streaming, having an impact on the tubuloglomerular feedback mechanism.
在通过体内戊二醛灌注或速冻-冷冻置换固定的小鼠致密斑（MD）中，其基底外侧间隙（BLIS）会扩张，这表明在正常运作的肾单位中致密斑细胞间隙可能是扩张的。在伴有“透明”管型的管腔阻塞的MD中，BLIS也会扩张。这一发现可能表明存在肾小球-致密斑的液体和溶质流动，对管球反馈机制有影响。
