Coelho Filho J C
Departamento de Patologia do Instituto Brasileiro para Investigação do Tórax (IBIT) Fundação José Silveira, Bahia, Brazil.
Rev Inst Med Trop Sao Paulo. 1990 Jan-Feb;32(1):63-6. doi: 10.1590/s0036-46651990000100011.
Six cases of a cavitary pulmonary ball formed by Actinomycetes are reported. They were observed in the state of Bahia, Brazil. All patients complained of cough and hemoptysis and the pathological study showed bronchiectasis and small cavities in the lungs. The lesions contained micro-colonies of Actinomyces, identified by morphology, staining properties and culture in two cases (thioglycolate media). In the six patients the disease was limited to the lungs. In one patient grains were found, within micro-abscesses in the surrounding parenchyma. Probably the invasion occurred due to ulceration of bronchial mucosa that was covered by granulation tissue. The author suggests that as in nocardiosis actinomycosis may have an invasive form, a saprophytic one may and colonize pulmonary cavities.
报告了6例由放线菌形成的肺空洞性球。这些病例来自巴西巴伊亚州。所有患者均有咳嗽和咯血症状，病理研究显示肺部存在支气管扩张和小空洞。病变中含有放线菌的微菌落，通过形态学、染色特性及在两例患者中（硫乙醇酸盐培养基）的培养得以鉴定。这6例患者的疾病均局限于肺部。在1例患者的周围实质微脓肿内发现了菌粒。推测侵袭可能是由于被肉芽组织覆盖的支气管黏膜溃疡所致。作者认为，如同诺卡菌病一样，放线菌病可能有侵袭性形式，也可能有腐生形式并定植于肺空洞。
