Phillips D P, Roye D P, Farcy J P, Leet A, Shelton Y A
Columbia-Presbyterian Medical Center, New York, New York.
Spine (Phila Pa 1976). 1990 Sep;15(9):942-5. doi: 10.1097/00007632-199009000-00019.
Seventy-eight patients were diagnosed with spinal muscular atrophy between 1969 and 1988. Scoliosis developed in 34 of these patients, an incidence of 60%. Thirty-one patients could be retrospectively reviewed by chart review or interview. The average follow-up was 11.5 years. Onset of scoliosis averaged 8.8 years. Twenty-two patients were treated nonsurgically and nine surgically. Patients had improved sitting balance and endurance after surgery. Complications of surgery included loss of correction in one patient, one pseudarthrosis, and one patient who required prolonged ventilatory support. The prolonged survival of patients with spinal muscular atrophy justifies aggressive orthopaedic management of scoliosis to prevent progression of deformity and improve sitting comfort.
1969年至1988年间，78例患者被诊断为脊髓性肌萎缩症。其中34例患者出现脊柱侧弯，发病率为60%。通过病历回顾或访谈对31例患者进行了回顾性分析。平均随访时间为11.5年。脊柱侧弯的平均发病年龄为8.8岁。22例患者接受了非手术治疗，9例接受了手术治疗。术后患者的坐位平衡和耐力有所改善。手术并发症包括1例矫正丢失、1例假关节形成，以及1例需要长期通气支持的患者。脊髓性肌萎缩症患者的长期存活证明了积极的脊柱侧弯矫形治疗对于防止畸形进展和提高坐位舒适度是合理的。
