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本文引用的文献

1
Definition of Tweener: Consensus Among Experts in Treating Early-onset Scoliosis.“过渡型”的定义:早期脊柱侧弯治疗专家的共识
J Pediatr Orthop. 2023 Mar 1;43(3):e215-e222. doi: 10.1097/BPO.0000000000002321. Epub 2022 Dec 12.
2
Reliability of Preoperative Supine Versus Bending Radiographs in Estimating the Structural Nature of Curves in EOS.术前仰卧位与弯曲位EOS X线片在评估脊柱侧弯结构性质中的可靠性
J Pediatr Orthop. 2023 Feb 1;43(2):70-75. doi: 10.1097/BPO.0000000000002305. Epub 2022 Dec 1.
3
Definitive fusions are better than growing rod procedures for juvenile patients with cerebral palsy and scoliosis: a prospective comparative cohort study.明确的融合术优于生长棒手术治疗脑瘫合并脊柱侧弯的青少年患者:一项前瞻性对照队列研究。
Spine Deform. 2023 Jan;11(1):145-152. doi: 10.1007/s43390-022-00577-7. Epub 2022 Sep 26.
4
Trends in the Utilization of Implants in Index Procedures for Early Onset Scoliosis From the Pediatric Spine Study Group.索引程序中植入物使用趋势:来自儿科脊柱研究组的早发性脊柱侧凸研究。
J Pediatr Orthop. 2022 Oct 1;42(9):e912-e916. doi: 10.1097/BPO.0000000000002221. Epub 2022 Aug 8.
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Genetic animal modeling for idiopathic scoliosis research: history and considerations.特发性脊柱侧凸研究的遗传动物模型:历史与考虑。
Spine Deform. 2022 Sep;10(5):1003-1016. doi: 10.1007/s43390-022-00488-7. Epub 2022 Apr 16.
6
Clinical Issues in Indication, Correction, and Outcomes of the Surgery for Neuromuscular Scoliosis: Narrative Review in Pedicle Screw Era.神经肌肉型脊柱侧弯手术的适应症、矫正及手术效果相关临床问题:椎弓根螺钉时代的叙述性综述
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Treatment of infantile idiopathic scoliosis using a novel thoracolumbosacral orthosis: a case report.使用新型胸腰骶椎矫形器治疗婴儿特发性脊柱侧凸:病例报告。
J Med Case Rep. 2022 Jan 5;16(1):20. doi: 10.1186/s13256-021-03168-8.
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No Difference in the Rates of Unplanned Return to the Operating Room Between Magnetically Controlled Growing Rods and Traditional Growth Friendly Surgery for Children With Cerebral Palsy.脑瘫儿童使用磁控生长棒与传统生长友好型手术的非计划性手术室重返率无差异。
J Pediatr Orthop. 2022 Feb 1;42(2):100-108. doi: 10.1097/BPO.0000000000001892.
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Magnetically Controlled Growing Rods Graduation: Deformity Control with High Complication Rate.磁力控制生长棒矫形:高并发症率的畸形控制。
Spine (Phila Pa 1976). 2021 Oct 15;46(20):E1105-E1112. doi: 10.1097/BRS.0000000000004044.
10
Efficacy of bracing in early infantile scoliosis: a 5-year prospective cohort shows that idiopathic respond better than secondary-2021 SOSORT award winner.支具治疗早期婴儿型脊柱侧凸的疗效:一项为期5年的前瞻性队列研究表明,特发性脊柱侧凸的疗效优于继发性脊柱侧凸——2021年SOSORT奖得主。
Eur Spine J. 2021 Dec;30(12):3498-3508. doi: 10.1007/s00586-021-06889-y. Epub 2021 Jun 6.

早发性脊柱侧弯的诊断与治疗进展

Update on the Diagnosis and Management of Early-onset Scoliosis.

作者信息

Ashebo Leta, Anari Jason B, Cahill Patrick J

机构信息

Division of Orthopaedics, Children's Hospital of Philadelphia, 3500 Civic Center Blvd, Philadelphia, PA, 19142, USA.

出版信息

Curr Rev Musculoskelet Med. 2023 Oct;16(10):447-456. doi: 10.1007/s12178-023-09848-w. Epub 2023 Aug 24.

DOI:10.1007/s12178-023-09848-w
PMID:37615932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10497459/
Abstract

PURPOSE OF REVIEW

In this article, we review the most recent advancements in the approaches to EOS diagnosis and assessment, surgical indications and options, and basic science innovation in the space of early-onset scoliosis research.

RECENT FINDINGS

Early-onset scoliosis (EOS) covers a diverse, heterogeneous range of spinal and chest wall deformities that affect children under 10 years old. Recent efforts have sought to examine the validity and reliability of a recently developed classification system to better standardize the presentation of EOS. There has also been focused attention on developing safer, informative, and readily available imaging and clinical assessment tools, from reduced micro-dose radiographs, quantitative dynamic MRIs, and pulmonary function tests. Basic science innovation in EOS has centered on developing large animal models capable of replicating scoliotic deformity to better evaluate corrective technologies. And given the increased variety in approaches to managing EOS in recent years, there exist few clear guidelines around surgical indications across EOS etiologies. Despite this, over the past two decades, there has been a considerable shift in the spinal implant landscape toward growth-friendly instrumentation, particularly the utilization of MCGR implants. With the advent of new biological and basic science treatments and therapies extending survivorship for disease etiologies associated with EOS, the treatment for EOS has steadily evolved in recent years. With this has come a rising volume and variation in management options for EOS, as well as the need for multidisciplinary and creative approaches to treating patients with these complex and heterogeneous disorders.

摘要

综述目的

在本文中,我们回顾了早发性脊柱侧弯(EOS)诊断与评估方法、手术适应症与选择以及该领域基础科学创新方面的最新进展。

最新发现

早发性脊柱侧弯(EOS)涵盖了一系列影响10岁以下儿童的多样、异质性的脊柱和胸壁畸形。近期研究致力于检验一种新开发的分类系统的有效性和可靠性,以更好地规范EOS的表现形式。人们还集中关注开发更安全、信息丰富且易于获得的成像和临床评估工具,包括减少微剂量X线片、定量动态磁共振成像和肺功能测试。EOS的基础科学创新主要集中在开发能够复制脊柱侧弯畸形的大型动物模型,以更好地评估矫正技术。鉴于近年来EOS治疗方法的多样性增加,针对EOS各种病因的手术适应症几乎没有明确的指导方针。尽管如此,在过去二十年中,脊柱植入物领域已发生了相当大的转变,朝着有利于生长的器械发展,尤其是MCGR植入物的应用。随着新的生物和基础科学治疗方法的出现,以及与EOS相关疾病病因的生存期延长,近年来EOS的治疗方法不断发展。随之而来的是EOS管理选择的数量增加和变化,以及需要采用多学科和创造性方法来治疗这些复杂和异质性疾病的患者。