Kowal M, Rupniewska Z M
Kliniki Hematologii Instytutu Chorób Wewnetrznych AM w Lublinie.
Acta Haematol Pol. 1990 Jan-Jun;21(1):32-45.
In a group of 23 patients with chronic lymphocytic leukaemia in 1-4 clinical stages of the disease according to Rai et al (34) classification, mostly untreated (only 5 treated) considerable heterogeneity was found as evidenced by: variability of the morphological patterns of bone marrow, differences of immunological phenotypes of peripheral blood lymphocytes between individual cases, --coexistence of the features of maturity and immaturity in the populations of peripheral blood lymphocytes in the same case.
在一组23例慢性淋巴细胞白血病患者中,根据Rai等人(34)的分类,疾病处于1 - 4个临床阶段,大多数患者未经治疗(仅5例接受过治疗),发现存在相当大的异质性,表现为:骨髓形态模式的变异性、个别病例外周血淋巴细胞免疫表型的差异、同一病例外周血淋巴细胞群体中成熟和不成熟特征的共存。