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N-（2-氨基吡啶-3-基）-4-甲基-N-（4-甲基苯基磺酰基）苯磺酰胺

N-(2-Amino-pyridin-3-yl)-4-methyl-N-(4-methyl-phenyl-sulfon-yl)benzene-sulfonamide.

作者信息

Taher Abu, Smith Vincent J

机构信息

Department of Chemistry and Polymer Science, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o1136. doi: 10.1107/S1600536812010872. Epub 2012 Mar 21.

DOI:10.1107/S1600536812010872
PMID:22606085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3344082/
Abstract

The title compound, C(19)H(19)N(3)O(4)S(2), was prepared by the reaction of 2,3-diamino-pyridine with tosyl chloride in a mixture of dichloro-methane-pyridine as solvent. In the crystal, mol-ecules associate via pairs of N-H⋯N hydrogen bonds, forming a centrosymmetric eight-membered {⋯HNCN}(2) synthon. The dihedral angles between the amino-pyridine ring and the tosyl benzene rings are 50.01 (6) and 32.01 (4)°.

摘要

标题化合物C(19)H(19)N(3)O(4)S(2)是通过2,3-二氨基吡啶与对甲苯磺酰氯在二氯甲烷-吡啶混合溶剂中反应制备的。在晶体中，分子通过N-H⋯N氢键对缔合，形成中心对称的八元{⋯HNCN}(2)合成子。氨基吡啶环与对甲苯磺酰苯环之间的二面角为50.01 (6)°和32.01 (4)°。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81be/3344082/3733cf6bffc1/e-68-o1136-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81be/3344082/f07940a61310/e-68-o1136-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81be/3344082/3733cf6bffc1/e-68-o1136-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81be/3344082/f07940a61310/e-68-o1136-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81be/3344082/3733cf6bffc1/e-68-o1136-fig2.jpg

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