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晶状体溶解性青光眼的不寻常表现:模拟微生物性角膜炎。

Unusual presentation of phacolytic glaucoma: simulating microbial keratitis.

作者信息

Sahu Srikant Kumar, Keswarwani Siddharth, Mittal Ruchi

机构信息

Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Orissa 751024, India.

出版信息

Case Rep Ophthalmol Med. 2011;2011:850919. doi: 10.1155/2011/850919. Epub 2011 Dec 20.

Abstract

The differential diagnoses for phacolytic glaucoma are acute angle closure glaucoma, open angle glaucoma with uveitis, neovascular glaucoma, and glaucoma secondary to trauma. We report an unusual case where the dislocated cataractous lens firmly adherent to the corneal endothelium evoked a cellular reaction similar to phacolytic glaucoma but clinically appeared like a deep corneal abscess. The 73-year-old lady presented with severe photophobia, pain, and redness in the left eye for two months despite being on antibiotics and antifungals. Anterior chamber wash revealed a cataractous lens buried within the infiltrate, which was removed and sent for histopathological examination. Postoperatively she was treated with topical ofloxacin, homatropine, dorzolamide, timolol, and tapering dose of steroids. Histological confirmation of inflammation, histiocytic response, and giant cells around the lens material confirmed the ongoing phacolytic process. Photophobia, pain, and redness subsided following removal of the lens and surrounding cellular reaction. At her last visit, four months after surgery, she was comfortable.

摘要

晶状体溶解性青光眼的鉴别诊断包括急性闭角型青光眼、伴有葡萄膜炎的开角型青光眼、新生血管性青光眼以及外伤性青光眼。我们报告了一例不寻常的病例,脱位的白内障晶状体牢固地附着于角膜内皮,引发了类似于晶状体溶解性青光眼的细胞反应,但临床外观却像一个深层角膜脓肿。这位73岁的女性尽管使用了抗生素和抗真菌药物,但左眼仍出现严重畏光、疼痛和眼红症状达两个月。前房冲洗显示一个白内障晶状体埋于浸润物中,将其取出并送去做组织病理学检查。术后她接受了局部氧氟沙星、后马托品、多佐胺、噻吗洛尔治疗以及逐渐减量的类固醇治疗。对晶状体物质周围炎症、组织细胞反应和巨细胞的组织学确认证实了正在进行的晶状体溶解过程。取出晶状体及周围细胞反应后,畏光、疼痛和眼红症状消退。在术后四个月的最后一次随访时,她情况良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d343/3350162/8ce6b3ec5286/CRIM.OPHMED2011-850919.001.jpg

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