McClellan K, Coster D J
Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia.
Br J Ophthalmol. 1987 Oct;71(10):734-6. doi: 10.1136/bjo.71.10.734.
A previously healthy 53-year-old man had keratitis of the right eye for six months, unresponsive to topical medical therapy. Acanthamoeba was grown from tissue obtained by corneal biopsy and from aqueous from an anterior chamber tap. The patient was treated with propamidine isethionate 0.1% drops and dibromopropamidine isethionate 0.15% ointment, and after two and a half months the ocular inflammation was continuing to resolve. This case supports a role for the diamidines in the treatment of acanthamoebic keratitis.
一名既往健康的53岁男性右眼患角膜炎6个月，局部药物治疗无效。从角膜活检获取的组织以及前房穿刺抽取的房水中培养出棘阿米巴。患者接受0.1%的依西酸丙脒滴眼液和0.15%的二溴丙脒软膏治疗，两个半月后眼部炎症持续消退。该病例支持双脒类药物在棘阿米巴性角膜炎治疗中的作用。
