Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 9, Zurich, Switzerland.
J Agric Food Chem. 2012 Jun 20;60(24):6123-30. doi: 10.1021/jf300781a. Epub 2012 Jun 11.
Polished and cargo rice, wild rice, rice bran, corn bran, and wheat bran were subjected to a static in vitro digestion model, to monitor changes in their steryl ferulate content and composition. Free sterols, possible hydrolysis products of steryl ferulates, were also measured. Additionally, steryl ferulate bioaccessibility was calculated as the percentage of steryl ferulates liberated from the grain matrix into the digestive juice. Steryl ferulate content ranged between 6.1 and 3900 μg/g and decreased by 1-63% due to digestion. A parallel increase in free sterols of more than 70% was observed in all samples. Additionally, bioaccessibility of steryl ferulates was found to be almost negligible. These findings suggest that intestinal enzymes immediately hydrolyze steryl ferulates, which are liberated from the grain matrix, and thus they are practically unavailable for absorption in the small intestine. This further indicates that the hydrolysis products of steryl ferulates could be bioactive in the gut.
抛光大米和糙米、野生稻、米糠、玉米糠和麦麸分别采用静态体外消化模型，以监测其阿魏酰甾醇含量和组成的变化。还测量了游离甾醇，即阿魏酰甾醇的可能水解产物。此外，还计算了阿魏酰甾醇的生物利用度，即从谷物基质中释放到消化液中的阿魏酰甾醇的百分比。阿魏酰甾醇的含量在 6.1 至 3900μg/g 之间，由于消化作用减少了 1-63%。所有样品中游离甾醇的含量都增加了 70%以上。此外，还发现阿魏酰甾醇的生物利用度几乎可以忽略不计。这些发现表明，肠道酶立即水解从谷物基质中释放出来的阿魏酰甾醇，因此它们在小肠中几乎无法被吸收。这进一步表明，阿魏酰甾醇的水解产物在肠道中可能具有生物活性。
