三氯醋酸对早产儿视网膜病变中内皮抑素样蛋白的影响。
The influence of triamcinolone on endostatin-like proteins in oxygen-induced retinopathy of prematurity.
出版信息
Exp Eye Res. 2012 Jul;100:86-7. doi: 10.1016/j.exer.2012.04.017. Epub 2012 May 16.
PMID:22609274
Abstract
In the murine model of oxygen-induced retinopathy of prematurity, early treatment (right after oxygen exposure) with triamcinolone reduced neovascularization and subsequently endostatin presence. Late treatment (3 days after oxygen exposure) limited pathological vascular sprouting, not interfering with normal vascularization of the retina. The effects remained unilateral in the treated eyes.
摘要
在氧诱导的早产儿视网膜病变的鼠模型中，曲安奈德的早期治疗（在氧暴露后立即进行）可减少新生血管形成并随后增加内皮抑素的存在。晚期治疗（氧暴露后 3 天）限制病理性血管发芽，但不干扰视网膜的正常血管化。在治疗的眼中，这些效果仍然是单侧的。
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