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脑动脉瘤:377例病例的评估(1956 - 1982年)

Cerebral aneurysms: assessment of 377 cases (1956-1982).

作者信息

Hey O, Dei-Anang K, Borges G, Schürmann K, Müller W

机构信息

Department of Neurosurgery, University Hospital, Mainz, DBR.

出版信息

Arq Neuropsiquiatr. 1990 Jun;48(2):225-30. doi: 10.1590/s0004-282x1990000200015.

Abstract

A review of 177 patients with cerebral aneurysms is made, out of whom 106 with ruptured aneurysms were examined, whose operational timing and prognostic chances were well documented (group B, 1979-1982) and in part updated to 1984. Furthermore, relevant data of a previous series of 200 cases of cerebral aneurysm, treated between 1956-1978 were used (group A). The patients were graded according to Hunt and Hess, assessing the risks involved. The percentages of recurrent bleeding were in group A 36.5% and 28% in group B. The incidence of vasospasm (as seen in angiography) was in group B 39.6% (42/106 patients). The highest rate of vasospasm in the spasm group division B was found to occur in the second and third week after subarachnoid haemorrhage and amounted to 64.7% and 62.5%. A pre-operatively present vasospasm had no negative effects on the mortality rate, but influenced the outcome for the survivors effectively. The total mortality in group A was 22.5% and in group B 11.7%. Timing of the operation among patients in Hunt and Hess-grades I and II needs to discussion. The surgical position of patients in grade V is also certain. What remains to be discussed and needs attention is grade III and patients in grade IVa. Here the time of operative intervention must be planned individually depending on the course of the neurological status.

摘要

对177例脑动脉瘤患者进行了回顾性研究,其中106例为动脉瘤破裂患者,对其手术时机和预后情况有详细记录(B组,1979 - 1982年),部分数据更新至1984年。此外,还采用了此前1956 - 1978年间治疗的200例脑动脉瘤患者的相关数据(A组)。根据Hunt和Hess分级法对患者进行分级,评估所涉及的风险。A组再出血率为36.5%,B组为28%。血管痉挛发生率(血管造影所见)在B组为39.6%(106例患者中有42例)。在B组血管痉挛分组中,蛛网膜下腔出血后第二周和第三周血管痉挛发生率最高,分别为64.7%和62.5%。术前存在的血管痉挛对死亡率无负面影响,但对幸存者的预后有显著影响。A组总死亡率为22.5%,B组为11.7%。Hunt和Hess分级为I级和II级患者的手术时机有待讨论。V级患者的手术体位也已确定。有待讨论且需要关注的是III级和IVa级患者。在此,手术干预时间必须根据神经状态的变化进行个体化规划。

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