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在环境温度下，无催化剂使用甘油绿色高效合成 2-芳基苯并噻唑。

Green and highly efficient synthesis of 2-arylbenzothiazoles using glycerol without catalyst at ambient temperature.

机构信息

Chemistry Department, Faculty of Science, El-Minia University, El-Minia 61519, Egypt.

出版信息

Molecules. 2012 May 18;17(5):6011-9. doi: 10.3390/molecules17056011.

DOI:10.3390/molecules17056011
PMID:22609790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6268630/
Abstract

A one-pot and clean synthesis of 2-arylbenzothiazoles via the ambient temperature reaction of 2-aminothiophenols and aromatic aldehydes without catalyst in glycerol as a green solvent has been reported.

摘要

本文报道了一种在无催化剂、绿色溶剂甘油中，通过 2-氨基苯硫酚和芳香醛在室温下的一锅干净合成 2-芳基苯并噻唑的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/6268630/0f4ce3499495/molecules-17-06011-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/6268630/9556437a479f/molecules-17-06011-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/6268630/0f4ce3499495/molecules-17-06011-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/6268630/9556437a479f/molecules-17-06011-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f66/6268630/0f4ce3499495/molecules-17-06011-sch002.jpg

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Acta Chim Slov. 2010 Sep;57(3):741-5.
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Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating.在微波控制加热下，5-氨基吡唑、环状 1,3-二酮和二甲氧基甲烷二甲缩醛的多组分反应中的区域选择性。
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Aerobic visible-light photoredox radical C-H functionalization: catalytic synthesis of 2-substituted benzothiazoles.
A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation.
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Molecules. 2018 Mar 9;23(3):619. doi: 10.3390/molecules23030619.
有氧可见光照光氧化还原自由基 C-H 官能化：2-取代苯并噻唑的催化合成。
Org Lett. 2012 Jan 6;14(1):98-101. doi: 10.1021/ol2028866. Epub 2011 Dec 6.
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