基因专利的危险。
The perils of gene patents.
机构信息
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
出版信息
Clin Pharmacol Ther. 2012 Jun;91(6):969-71. doi: 10.1038/clpt.2012.6.
Abstract
I argue here that gene patents, and patented genetic tests based on them, are a very bad idea. First, I discuss whether genes can reasonably be the subject of patents in the first place; I maintain that the answer is no. Second, I explain how gene patents interfere with scientific progress, slowing down the development of new cures and treatments for genetic diseases.
摘要
我在这里主张，基因专利以及基于这些专利的基因检测是一个非常糟糕的主意。首先，我将讨论基因是否能被合理地授予专利；我认为答案是否定的。其次，我将解释基因专利如何干扰科学进步，减缓治疗遗传疾病的新方法和新疗法的发展。
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本文引用的文献
1
Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986. 46: 705-716.多种核因子与免疫球蛋白增强子序列相互作用。《细胞》1986年。第46卷：705 - 716页。
J Immunol. 2006 Dec 1;177(11):7485-96.
2
Intellectual property. Enhanced: intellectual property landscape of the human genome.知识产权。强化：人类基因组的知识产权格局。
Science. 2005 Oct 14;310(5746):239-40. doi: 10.1126/science.1120014.
3
Population genetics of BRCA1 and BRCA2.BRCA1和BRCA2的群体遗传学
Am J Hum Genet. 1997 May;60(5):1013-20.
4
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes.一种与免疫球蛋白基因转录控制元件中的保守序列基序结合的核因子。
Nature. 1986;319(6049):154-8. doi: 10.1038/319154a0.
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