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[采用佩林和麦克劳林技术治疗脑脊液分流感染。11例病例分析]

[Treatment of cerebrospinal fluid shunt infections using the Perrin and McLaurin technique. Analysis of 11 cases].

作者信息

Vilalta J, Sahuquillo J, Castaño C, Bosch J, Rubio E

机构信息

Servicio de Neurocirugía Hospital Vall d'Hebron, Barcelona.

出版信息

Neurologia. 1990 Jun-Jul;5(6):188-91.

PMID:2261189
Abstract

Eleven patients with shunt infection (SI) of the cerebrospinal fluid in whom the SI was withdrawn and replaced by a new SI system with reservoir and intraventricular and parenteral antibiotic treatment were reported. The diagnosis was made by culture of the components of the SI and, or, the cerebrospinal fluid. In 9 cases the agent was a staphylococcus. The different therapeutic trials to treat SI infections can be summarized as follows: a) replacement of the SI by an external drainage, antibiotics, and reinsertion of the SI when the cerebrospinal fluid was sterilized; b) withdrawal of the SI and placement of a new SI in the same surgical procedure associated with intraventricular and systemic antibiotic treatment; and c) treatment with intraventricular and, or, systemic antibiotics. It has been demonstrated that the surgical approach (a and b) is more effective. In our series the procedure indicated in B was followed by the control of the infection in all cases. The follow-up of the surgical treatment was 1-3 years. The most currently used SI was the ventriculoperitoneal bypass. Their main complications are pseudocysts which are easily recognized by of abdominal echography and frequently revealed SI infection. Diagnosis and treatment of SI infections should take into account the type of complications and the most appropriate collaboration with other clinical departments.

摘要

报告了11例脑脊液分流感染(SI)患者,这些患者的分流装置被取出,并用带有储液器的新分流系统替换,并进行了脑室内和肠外抗生素治疗。通过对分流装置组件和/或脑脊液进行培养来做出诊断。9例患者的病原体为葡萄球菌。治疗SI感染的不同治疗试验可总结如下:a)用外部引流替换分流装置、使用抗生素,并在脑脊液无菌后重新插入分流装置;b)在同一手术过程中取出分流装置并放置新的分流装置,同时进行脑室内和全身抗生素治疗;c)使用脑室内和/或全身抗生素进行治疗。已证明手术方法(a和b)更有效。在我们的系列病例中,采用b中所述程序后,所有病例的感染均得到控制。手术治疗的随访时间为1至3年。目前最常用的分流装置是脑室腹腔分流术。其主要并发症是假性囊肿,通过腹部超声检查很容易识别,且常提示分流感染。SI感染的诊断和治疗应考虑并发症的类型以及与其他临床科室最恰当的协作。

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