Kaojarern Sming, Pattanaprateep Oraluck
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2012 Apr;95(4):519-25.
Generic substitution is a mechanism for reducing drug expenditure in many healthcare settings. Ramathibodi, a teaching hospital, has introduced mandatory generic drug substitution (228 items) for health schemes in inpatient service since September 1, 2009.
Explore prescribing patterns in overall and by patients' health schemes between Thai fiscal year 2009 and 2010, and estimate possible saving if this policy was extended to the outpatient service.
Prescribing data and registered populations between October 1, 2008 and September 30, 2010 were retrieved from the database and analyzed.
Original and generic expenditure rose 8.42 and 8.61%from 2009 to 2010 respectively. Among 228 mandatory items, more original was switched to generic drugs, both in terms of value (6.5 to 7.2%) and in terms of volume (32.5 to 33.8%). Some inpatients, mainly civil servants and self-pay patients, requested the original from the outpatient service where the mandatory substitution was not applied. If the policy were extended through all services, the government would save approximately 306.5 million Baht (US$ 10.1 million) per year However the hospital would reduce its profit by 53.1 million Baht (US$ 1.7 million).
After the policy was launched, more original mandatory drugs were switched to generic. To gain more saving, the policy may be expanded to outpatient service, and/or mandatory drug list should be reviewed periodically.
在许多医疗环境中,通用名药物替代是一种降低药物支出的机制。拉玛蒂博迪医院作为一家教学医院,自2009年9月1日起已在住院服务的健康计划中引入了强制性通用名药物替代(228种药品)。
探究泰国2009财年至2010财年期间总体及按患者健康计划划分的处方模式,并估计若该政策扩展至门诊服务可能节省的费用。
从数据库中检索并分析2008年10月1日至2010年9月30日期间的处方数据和登记人口。
从2009年到2010年,原研药支出和通用名药物支出分别增长了8.42%和8.61%。在228种强制性替代药品中,无论是价值方面(从6.5%至7.2%)还是数量方面(从32.5%至33.8%),更多的原研药被替换为通用名药物。一些住院患者,主要是公务员和自费患者,在不适用强制性替代的门诊服务中要求使用原研药。如果该政策扩展至所有服务,政府每年将节省约3.065亿泰铢(1010万美元)。然而,医院的利润将减少5310万泰铢(170万美元)。
该政策实施后,更多的原研强制性药物被替换为通用名药物。为了获得更多节省,该政策可扩展至门诊服务,和/或应定期审查强制性药物清单。