Energy Materials Laboratory, School of Chemistry, University of East Anglia , Norwich NR4 7TJ, United Kingdom.
ACS Appl Mater Interfaces. 2012 Jun 27;4(6):3285-92. doi: 10.1021/am300642m. Epub 2012 Jun 4.
Stable and brightly luminescent amine-terminated Si nanoparticles (SiNPs) have been synthesized from electrochemically etched porous silicon (PSi). The surface amine termination was confirmed by FTIR, NMR, and XPS studies. The mean diameter of the crystal core of 4.6 nm was measured by transmission electron microscopy (TEM), which is in a good agreement with the size obtained by dynamic light scattering (DLS). The dry, amine-terminated product can be obtained from bulk silicon wafers in less than 4 h. This represents a significant improvement over similar routines using PSi where times of >10 h are common. The emission quantum yield was found to be about 22% and the nanoparticles exhibited an exceptional stability over a wide pH range (4-14). They are resistant to aging over several weeks. The amine-terminated SiNPs showed no significant cytotoxic effects toward HepG2 cells, as assessed with MTT assays.
已从电化学刻蚀的多孔硅（PSi）中合成出稳定且发光亮度高的胺封端硅纳米粒子（SiNPs）。通过傅里叶变换红外光谱（FTIR）、核磁共振（NMR）和 X 射线光电子能谱（XPS）研究证实了表面胺封端。通过透射电子显微镜（TEM）测量的晶体核的平均直径为 4.6nm，这与动态光散射（DLS）获得的尺寸非常吻合。干燥的胺封端产物可以在不到 4 小时内从块状硅片获得。与使用 PSi 的类似方法相比，这是一个重大改进，使用 PSi 时通常需要超过 10 小时的时间。量子产率约为 22%，并且纳米粒子在很宽的 pH 范围内（4-14）表现出异常的稳定性。它们可以在数周内抵抗老化。MTT 测定法评估表明，胺封端的 SiNPs 对 HepG2 细胞没有明显的细胞毒性作用。
