检测和研究诱变剂暴露后DNA序列变化的可能方法：突变DNA的磁富集。
Possible methodologies for the detection and study of DNA sequence changes following mutagen exposure: magnetic enrichment in mutant DNA.
作者信息
Bridges B A, Carr A M, Lehmann A R
机构信息
MRC Cell Mutation Unit, University of Sussex, Falmer, Brighton, UK.
出版信息
Mutagenesis. 1990 Nov;5(6):523-4. doi: 10.1093/mutage/5.6.523.
PMID:2263210
Abstract
The restriction site mutation method described by Parry et al. (1990) for isolating mutant sequences directly from DNA is discussed and an additional enrichment step proposed using magnetic beads.
摘要
本文讨论了Parry等人（1990年）描述的用于直接从DNA中分离突变序列的限制性酶切位点突变方法，并提出了使用磁珠的额外富集步骤。
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