Department of Medicine C, Sheba Medical Center, Center for Geographic Medicine, Tel Hashomer 52621, Israel.
Infect Dis Clin North Am. 2012 Jun;26(2):479-96. doi: 10.1016/j.idc.2012.02.003. Epub 2012 Apr 17.
The viral hemorrhagic fever (VHF) syndrome is a potentially life-threatening infection typified by a combination of a capillary leak syndrome and bleeding diathesis. Most but not all agents causing VHF are arboviruses, with transmission to humans resulting from an arthropod bite. Agents of VHF affect humans on all continents. Population growth, urbanization, human activities, and even climate change all contribute to a continual flux in the epidemiology of many arboviruses. This review provides an overview of the epidemiology of arboviral infections and VHF, the main clinical syndromes, and their diagnosis and treatment.
病毒性出血热（VHF）综合征是一种潜在的危及生命的感染，其特征是毛细血管渗漏综合征和出血素质的组合。引起 VHF 的大多数但不是所有病原体都是虫媒病毒，通过节肢动物叮咬传播给人类。VHF 病原体影响所有大陆的人类。人口增长、城市化、人类活动甚至气候变化都导致许多虫媒病毒的流行病学不断变化。本综述提供了虫媒病毒感染和 VHF 的流行病学、主要临床综合征及其诊断和治疗的概述。
