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[细菌性眼内炎:拉巴特专科医院的回顾性临床与微生物学研究]

[Bacterial endophthalmitis: retrospective clinical and microbiological study in Rabat Specialty Hospital].

作者信息

Marcil S, Kabbaj H, Cherkaoui O, Nadah M, Alaoui A E, Seffar M

机构信息

Faculté de Médecine et de Pharmacie, Université Mohamed V Souissi, Rabat Institut, BP 6203, avenue Mohamed Belarbi El Alaoui, Rabat, Maroc.

出版信息

J Fr Ophtalmol. 2012 Sep;35(7):499-502. doi: 10.1016/j.jfo.2011.09.015. Epub 2012 May 26.

DOI:10.1016/j.jfo.2011.09.015
PMID:22634027
Abstract

OBJECTIVES

To study and discuss the epidemiological, clinical, microbiological, and risk factors of bacterial endophthalmitis treated in the Rabat Specialty Hospital ophthalmology department.

PATIENTS AND METHODS

This is a retrospective study over a period of 10 months of patients hospitalized for suspected acute infectious endophthalmitis. An intake form was completed for each patient. Each sample underwent direct examination and culture. All patients underwent the same protocol, providing for at least one intravitreal antibiotic injection and instillation of fortified eye drops.

RESULTS

Twenty cases of endophthalmitis were recorded during the study period. Decreased visual acuity, intraocular inflammation, pain and conjunctival hyperemia were found in all patients. The median onset of symptoms was 4 days. Vitreous tap or anterior chamber paracentesis was performed in all patients. Bacteria were found in seven samples (40%). Gram positive organisms accounted for 85% of positive cultures. Amphotericin B was required in four patients, and systemic antibiotic therapy in ten patients. Corticosteroid treatment was administered secondarily in eight patients.

DISCUSSION

In this retrospective series, epidemiological, clinical and microbiological data are consistent with those already published.

摘要

目的

研究并讨论拉巴特专科医院眼科治疗的细菌性眼内炎的流行病学、临床、微生物学及危险因素。

患者与方法

这是一项为期10个月的回顾性研究,研究对象为因疑似急性感染性眼内炎住院的患者。为每位患者填写一份入院表格。每个样本都进行了直接检查和培养。所有患者均接受相同的治疗方案,包括至少一次玻璃体内抗生素注射和强化眼药水滴注。

结果

研究期间记录了20例眼内炎病例。所有患者均出现视力下降、眼内炎症、疼痛和结膜充血。症状出现的中位时间为4天。所有患者均进行了玻璃体穿刺或前房穿刺。7个样本(40%)中发现了细菌。革兰氏阳性菌占阳性培养物的85%。4例患者需要使用两性霉素B,10例患者需要全身抗生素治疗。8例患者随后接受了皮质类固醇治疗。

讨论

在这个回顾性系列研究中,流行病学、临床和微生物学数据与已发表的数据一致。

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