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2-O-D-吡喃葡萄糖基-L-抗坏血酸的功能、应用及生产

Functions, applications and production of 2-O-D-glucopyranosyl-L-ascorbic acid.

作者信息

Han Ruizhi, Liu Long, Li Jianghua, Du Guocheng, Chen Jian

机构信息

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

出版信息

Appl Microbiol Biotechnol. 2012 Jul;95(2):313-20. doi: 10.1007/s00253-012-4150-9. Epub 2012 May 26.

Abstract

Vitamin C (VC) is an essential nutrient that cannot be synthesized by the human body. Due to its extreme instability, various VC derivatives have been developed in an attempt to improve stability while retaining the same biological activity. One of the most important VC derivatives, 2-O-D-glucopyranosyl-L-ascorbic acid (AA-2G), has attracted increasing attention in recent years with a wide range of applications in cosmetics, food, and medicine. In this mini-review, we first introduce the types and properties of different VC glycosyl derivatives. Next, we provide an overview of the functions and applications of AA-2G. Finally, we discuss in-depth the current status and future prospects of AA-2G production by biotransformation.

摘要

维生素C(VC)是人体无法合成的必需营养素。由于其极不稳定,人们开发了各种VC衍生物,试图在保持相同生物活性的同时提高稳定性。2-O-D-吡喃葡萄糖基-L-抗坏血酸(AA-2G)是最重要的VC衍生物之一,近年来受到越来越多的关注,在化妆品、食品和医药领域有广泛应用。在本综述中,我们首先介绍不同VC糖基衍生物的类型和性质。接下来,我们概述AA-2G的功能和应用。最后,我们深入讨论通过生物转化生产AA-2G的现状和未来前景。

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