Kim Chul, Choi Hee Eun, Kim Byung Ok, Lim Min Ho
Department of Rehabilitation Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 139-707, Korea.
Ann Rehabil Med. 2012 Apr;36(2):254-61. doi: 10.5535/arm.2012.36.2.254. Epub 2012 Apr 30.
To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES).
Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a control group. The CR group received six to eight weeks of early cardiac rehabilitation program in a hospital setting, and sustained a self-exercise program for six months in a community. The control group was instructed to exercise by themselves after leaving the hospital. Nine months after the first onset of disease, we implemented a coronary angiography and compared the two groups. In addition, we divided the patients into three subgroups according to the generation of DES, and compared the rate of restenosis between the CR group and control group within these three subgroups.
At 9 months, in-stent restenosis, measured as an in-segment late luminal loss (LLL) of the stented coronary area, was smaller in the CR group (n=52) 0.16±0.42 mm compared to the control group (n=51) 0.39±0.78 mm (p<0.05). A reduction of LLL in the CR group compared to the control group was consistent among the three different generations of DES.
The CR program is strongly associated with a significant reduction in LLL in the stented coronary segments, regardless of the generation of DES.
比较心脏康复（CR）组和对照组在三代不同药物洗脱支架（DES）中的再狭窄率。
纳入因急性冠状动脉综合征接受DES治疗的患者。将他们分为CR组和对照组。CR组在医院环境中接受6至8周的早期心脏康复计划，并在社区中持续进行6个月的自我锻炼计划。对照组在出院后自行锻炼。在首次发病9个月后，我们进行了冠状动脉造影并比较了两组。此外，我们根据DES的代别将患者分为三个亚组，并比较了这三个亚组中CR组和对照组之间的再狭窄率。
在9个月时，以支架置入冠状动脉区域的节段内晚期管腔丢失（LLL）衡量的支架内再狭窄，CR组（n = 52）为0.16±0.42 mm，低于对照组（n = 51）的0.39±0.78 mm（p<0.05）。在三代不同的DES中，CR组与对照组相比LLL的降低是一致的。
无论DES的代别如何，CR计划与支架置入冠状动脉节段中LLL的显著降低密切相关。
