Gad Nader, Duvvuru Amulya, Burchgart Brook
Department of Obstetrics and Gynecology, Royal Darwin Hospital, Darwin, Northern Territory Flinders University, Adelaide, South Australia, Australia.
J Obstet Gynaecol Res. 2013 Jan;39(1):243-9. doi: 10.1111/j.1447-0756.2012.01888.x. Epub 2012 May 28.
To assess the outcome of the Prolift Gynecare (Ethicon, Somerville, NJ, USA) mesh repair in the treatment of pelvic organ prolapse. This includes the anatomical success, complication rate and effect on associated lower urinary tract symptoms.
Retrospective case analysis of the above outcomes of 41 Prolift mesh repairs performed on 40 women over a 5-year period by a single surgeon in a private hospital in Australia.
Successful anatomical correction and bulge symptom resolution were observed in 100% (2/2), 91.6% (11/12) and 100% (27/27) of anterior, posterior and total Prolift, respectively. Prolapse in a non-treated compartment occurred in one woman. Two patients developed postoperative hematomas requiring surgical evacuation; one of whom developed urinary retention for 2 weeks. Preoperative urinary symptoms were reported in 35/40 (92%) of women, 8 of whom reported only urge symptoms and experienced complete resolution after Prolift. Resolution of stress urinary incontinence in women who had urodynamic stress incontinence with and without urge symptoms was reported in 60% (12/20) and 20% (1/5), respectively. This represented 62.5% (10/16) and 33.3% (3/9) of women who had total Prolift and posterior Prolift respectively. Average follow-up periods were 7 and 39 weeks in 38 and 18 women, respectively.
This study shows that Prolift procedure is safe and effective in women with severe pelvic organ prolapse with resolution of most of the bulge and urinary urge symptoms. Total Prolift was effective in the treatment of associated mixed urinary incontinence.
评估美国新泽西州萨默维尔市爱惜康公司生产的普理灵盆底修复系统（Prolift Gynecare）治疗盆腔器官脱垂的效果。这包括解剖学上的成功率、并发症发生率以及对相关下尿路症状的影响。
对澳大利亚一家私立医院的一名外科医生在5年时间里为40名女性进行的41例普理灵网片修复手术的上述结果进行回顾性病例分析。
在前位、后位和全盆底普理灵修复术中，分别有100%（2/2）、91.6%（11/12）和100%（27/27）实现了成功的解剖学矫正和膨出症状缓解。一名女性在未治疗的腔室出现了脱垂。两名患者术后出现血肿，需要手术引流；其中一人出现了2周的尿潴留。40名女性中有35名（92%）报告了术前尿路症状，其中8名仅报告了尿急症状，在接受普理灵修复术后症状完全缓解。在有和没有尿急症状的尿动力学压力性尿失禁女性中，压力性尿失禁的缓解率分别为60%（12/20）和20%（1/5）。这分别占接受全盆底普理灵修复术和后位普理灵修复术女性的62.5%（10/16）和33.3%（3/9）。38名和18名女性的平均随访期分别为7周和39周。
本研究表明，普理灵手术对于患有严重盆腔器官脱垂的女性是安全有效的，可缓解大多数膨出和尿急症状。全盆底普理灵修复术对治疗相关的混合性尿失禁有效。
