Vyhnánek F, Hejzlar M, Procházka M, Pellar T, St'astná L, Silarová J, Kittnar E, Vedral T
Katedra chirurgie LFH UK, Praha.
Rozhl Chir. 1990 Oct;69(10):668-73.
The authors investigated the antibacterial action of cefuroxim in vitro and proved its relatively broad spectrum of action. Administration of the esterified form, Zinnat, produced very satisfactory therapeutic concentrations of cefuroxim in serum, bile tissue of operated gallbladders. The prophylactic administration of the combined parenteral and oral form of cefuroxim proved excellent in biliary surgery in twenty patients.
作者研究了头孢呋辛的体外抗菌作用，并证明了其相对广泛的抗菌谱。给予酯化形式的头孢呋辛酯（Zinnat）后，在血清、手术切除胆囊的胆汁组织中产生了非常令人满意的头孢呋辛治疗浓度。对20例患者进行的胆道手术中，联合胃肠外和口服形式的头孢呋辛预防性给药效果极佳。
