从川榛核中分离得到的两个新的生物碱半乳糖苷。

Two new alkaloid galactosides from the kernel of Prinsepia uniflora.

机构信息

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, PR China.

出版信息

Nat Prod Res. 2013 Apr;27(8):687-90. doi: 10.1080/14786419.2012.691487. Epub 2012 May 29.

DOI:10.1080/14786419.2012.691487

PMID:22640596

Abstract

Two new alkaloid galactosides have been isolated from the kernel of Prinsepia uniflora. Their structures were elucidated as 5-[(α-D-galactopyranosyloxy) methyl]-1H-pyrrole-2-carbaldehyde (1) and 6-[(α-D-galactopyranosyloxy) methyl]-3-pyridinol (2) by various spectroscopic means including HR-ESI-MS, IR, 1D and 2D NMR. The determined structures were characterized with a unit of galactose which is rarely seen in the previously isolated pyrrole and pyridinol compounds.

摘要

从川榛（Prunus uniflora）的核仁中分离得到两个新的生物碱半乳糖苷。通过各种光谱方法，包括高分辨电喷雾质谱（HR-ESI-MS）、红外光谱（IR）、一维和二维核磁共振（1D 和 2D NMR），确定了它们的结构分别为 5-[(α-D-半乳糖吡喃糖基氧基)甲基]-1H-吡咯-2-甲醛（1）和 6-[(α-D-半乳糖吡喃糖基氧基)甲基]-3-吡啶醇（2）。所确定的结构的特征是含有一个半乳糖单元，这在以前分离得到的吡咯和吡啶醇类化合物中很少见。