从 Maackia amurensis 的茎皮中分离得到的一种新的野靛碱型生物碱。

A new cytisine-type alkaloid from the stem bark of Maackia amurensis.

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

出版信息

Nat Prod Res. 2010 Oct;24(16):1499-502. doi: 10.1080/14786410903265561.

PMID:20835948

Abstract

One new cytisine-type alkaloid, [(3-hydroxy-6-pyridinyl)-methyl]-cytisine (1), was isolated from the stem bark of Maackia amurensis, together with five known alkaloids: cytisine, N-formylcytisine, N-(3-oxobutyl)cytisine, (-)-epibaptifoline and N-methylcytisine. The structure of 1 was elucidated based on spectral methods (IR, CD, 1D and 2D NMR, HR-ESI-MS and EI-MS).

摘要

从大果茶藨的茎皮中分离得到了一个新的烟碱型生物碱，[(3-羟基-6-吡啶基)-甲基]-烟碱（1），同时还分离得到了 5 个已知生物碱：烟碱、N-甲酰基烟碱、N-(3-氧代丁基)烟碱、(-)-表巴普啡林和 N-甲基烟碱。1 的结构是通过光谱方法（IR、CD、1D 和 2D NMR、HR-ESI-MS 和 EI-MS）阐明的。