Henni Mehdi, Ali David
Service de radiothérapie oncologie, Hôpital européen Georges-Pompidou, 75015 Paris.
Rev Prat. 2012 Apr;62(4):461-6.
More than half of all people with cancer are treated with radiation therapy. Over the last decade the technical advances, both in therapy beam precision and imaging, have greatly improved the therapeutic ratio and accuracy of modern radiotherapy. However, damaging healthy tissues near the tumor leads to radiation induced injury that develops immediately and continue to progress long after exposure to radiation. Recently dramatic advances have been made in understanding the determinant of tissue response to radiation exposure.
超过一半的癌症患者接受放射治疗。在过去十年中,无论是治疗束精度还是成像方面的技术进步,都极大地提高了现代放射治疗的治疗比率和准确性。然而,肿瘤附近的健康组织受到损伤会导致辐射诱发的损伤,这种损伤在辐射暴露后立即出现,并在暴露后很长时间内持续发展。最近,在理解组织对辐射暴露反应的决定因素方面取得了巨大进展。