Kucera H
I. Universitäts-Frauenklinik, Wien.
Wien Med Wochenschr. 1990 Oct 31;140(20):502-6.
The benefit of adjuvant radiotherapy of operated cervical and endometrial cancer is not clear. In a prospective trial of 571 endometrial cancers stage I, cases with poor prognosticators are treated additionally with external pelvic irradiation (Co 60, 56 Gy) and show nearly the same outcome as cases with good prognosticators and without such an adjuvant therapy. A benefit of adjuvant irradiation of cervical carcinoma stage I/b could only be shown in cases with similar histopathologic characteristics (tumor volume, grading, vessel invasion, lymphnode involvement). In a retrospective study 171 cases of cervical carcinoma were analyzed. With adjuvant external irradiation the relapse free interval was longer and 5-year survival better than without such an adjuvant therapy.
手术治疗的宫颈癌和子宫内膜癌辅助放疗的益处尚不明确。在一项针对571例I期子宫内膜癌的前瞻性试验中,预后不良的患者额外接受盆腔外照射(钴60,56戈瑞),其结果与预后良好且未接受此类辅助治疗的患者几乎相同。I/b期宫颈癌辅助放疗的益处仅在具有相似组织病理学特征(肿瘤体积、分级、血管侵犯、淋巴结受累)的病例中得到体现。在一项回顾性研究中,分析了171例宫颈癌病例。与未接受辅助放疗相比,接受辅助外照射的患者无复发生存期更长,5年生存率更高。