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肾胰联合移植:急性情况下关键影像学表现的评估

Kidney-pancreas transplantation: assessment of key imaging findings in the acute setting.

作者信息

Heller Matthew T, Hattoum Alexander

机构信息

Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite 3950 PUH S. Tower, Pittsburgh, PA 15213, USA.

出版信息

Emerg Radiol. 2012 Dec;19(6):527-33. doi: 10.1007/s10140-012-1054-z. Epub 2012 May 29.

DOI:10.1007/s10140-012-1054-z
PMID:22644061
Abstract

For patients with diabetes, insulin therapy can be an effective treatment for years. However, many diabetics eventually develop complications from the disease, including neuropathy, amputations, atherosclerosis, and kidney failure. While kidney failure can be managed with dialysis, difficulties with monitoring fluid intake and diet, bone loss, anemia, and venous access can be problematic for the patient. Due to the decreased life expectancy and difficulties of medical management of patients with diabetes and renal failure, combined renal-pancreas transplantation is an increasingly used option available to type 1 diabetics with concurrent renal failure due to refinements of surgical technique and immunosuppressive therapy. Due to the increasing number of kidney-pancreas transplant patients, longer post-transplant survival, and increasing number of hospitals performing the procedure, more transplant patients are having their care increasingly shifted away from the major transplant centers to general community hospitals. In many kidney-pancreas transplants patients who present to the emergency department for suspected transplant dysfunction, imaging plays a critical initial role in their diagnosis and management. Therefore, it has become increasingly important that community and emergency department radiologists be able to recognize the normal imaging appearance of renal-pancreas transplants and to identify acute findings.

摘要

对于糖尿病患者而言,胰岛素治疗多年来一直是一种有效的治疗方法。然而,许多糖尿病患者最终会出现该疾病的并发症,包括神经病变、截肢、动脉粥样硬化和肾衰竭。虽然肾衰竭可以通过透析来控制,但对患者来说,监测液体摄入量和饮食、骨质流失、贫血以及静脉通路方面的困难可能会成为问题。由于糖尿病和肾衰竭患者的预期寿命缩短以及医疗管理困难,由于手术技术和免疫抑制疗法的改进,肾胰联合移植越来越多地成为患有并发肾衰竭的1型糖尿病患者的一种选择。由于肾胰移植患者数量不断增加、移植后生存期延长以及进行该手术的医院数量增多,越来越多的移植患者的护理正逐渐从主要的移植中心转向普通社区医院。在许多因疑似移植功能障碍而到急诊科就诊的肾胰移植患者中,影像学在其诊断和管理中起着关键的初始作用。因此,社区和急诊科放射科医生能够识别肾胰移植的正常影像学表现并识别急性病变变得越来越重要。

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Kidney-pancreas transplantation: assessment of key imaging findings in the acute setting.肾胰联合移植:急性情况下关键影像学表现的评估
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Function of pancreas allografts more than 1 year following transplantation.移植后1年以上的胰腺同种异体移植功能。
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Review of immunosuppressive usage in pancreas transplantation.胰腺移植中免疫抑制剂使用情况综述。
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Transplantation for type 1 diabetes: radiologist's primer on islet, pancreas and pancreas-kidney transplantation imaging.1 型糖尿病的移植:关于胰岛、胰腺和胰肾移植成像的放射科医生入门。
Abdom Radiol (NY). 2024 Oct;49(10):3637-3665. doi: 10.1007/s00261-024-04368-8. Epub 2024 May 28.

本文引用的文献

1
Single-center experience with pancreas transplantation.胰腺移植的单中心经验。
Transplant Proc. 2012 May;44(4):925-8. doi: 10.1016/j.transproceed.2012.03.035.
2
Imaging of pancreas transplants: postoperative findings with clinical correlation.胰腺移植的影像学检查:术后表现与临床相关性
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Kidney and pancreas transplantation in the United States, 1998-2007: access for patients with diabetes and end-stage renal disease.1998 - 2007年美国的肾与胰腺移植:糖尿病和终末期肾病患者的获取情况
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Temporal evolution of emphysematous pyelonephritis in a renal allograft: imaging findings.肾移植中气肿性肾盂肾炎的时间演变:影像学表现
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Intravascular gas in the transplanted kidney: a sign of extensive graft necrosis.移植肾血管内气体:广泛移植肾坏死的征象
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Massive gastrointestinal hemorrhage due to rupture of a donor pancreatic artery pseudoaneurysm in a pancreas transplant patient.一名胰腺移植患者因供体胰腺动脉假性动脉瘤破裂导致大量胃肠道出血。
Clin Transplant. 2004 Feb;18(1):108-11. doi: 10.1111/j.1399-0012.2004.00111.x.
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