Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Eur J Pediatr. 2012 Aug;171(8):1247-55. doi: 10.1007/s00431-012-1753-1. Epub 2012 May 27.
Adolescence obesity and depression are increasingly prevalent and are associated with various health complications. The aim of this study was to examine the association between weight status (normal weight, overweight, and obese) and depressive symptoms in adolescents and to explore the probable mediators, including overweight perception, greater weight concern, and dietary restraint. During the period October 2010 to January 2011, we recruited 869 adolescents (47 % girls; median age, 15.7 years) from four randomly selected high schools in Taipei city. The students were stratified into normal weight, overweight, or obese groups according to age- and gender-specific body mass index standards. Depressive symptoms were defined in students with a score of 29 or greater on the Center for Epidemiologic Studies Depression Scale. Overall, weight status was significantly associated with depressive symptoms (P = 0.02). Weight status was strongly associated with perceived overweight, greater weight concern, and dietary restraint. Those three variables were also associated with depressive symptoms. The association between overweight and depressive symptoms (odds ratio, 2.23; 95 % confidence interval, 1.30-3.82) became weaker after controlling for perceived overweight, greater weight concern, and dietary restraint. The association between weight status and depressive symptoms in adolescents was partly mediated by perceived overweight, greater weight concern, and dietary restraint. Further prospective cohort studies are needed to explore the association between weight status and depressive symptoms.
青少年肥胖和抑郁日益普遍，与各种健康并发症有关。本研究旨在探讨青少年体重状况（正常体重、超重和肥胖）与抑郁症状之间的关系，并探讨可能的中介因素，包括超重感知、更大的体重担忧和饮食控制。在 2010 年 10 月至 2011 年 1 月期间，我们从台北市随机选择的四所高中招募了 869 名青少年（47%为女生；中位数年龄为 15.7 岁）。根据年龄和性别特异性的体重指数标准，学生被分层为正常体重、超重或肥胖组。抑郁症状是根据中心流行病学研究抑郁量表得分≥29 定义的。总体而言，体重状况与抑郁症状显著相关（P=0.02）。体重状况与超重感知、更大的体重担忧和饮食控制密切相关。这三个变量也与抑郁症状有关。控制超重感知、更大的体重担忧和饮食控制后，超重与抑郁症状之间的关联（比值比，2.23；95%置信区间，1.30-3.82）减弱。超重感知、更大的体重担忧和饮食控制在青少年体重状况与抑郁症状之间存在部分中介作用。需要进一步的前瞻性队列研究来探讨体重状况与抑郁症状之间的关系。
