State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Sci China Life Sci. 2012 May;55(5):404-14. doi: 10.1007/s11427-012-4321-z. Epub 2012 May 27.
Halophilic archaea (haloarchaea) inhabit hypersaline environments, tolerating extreme salinity, low oxygen and nutrient availability, and in some cases, high pH (soda lakes) and irradiation (saltern ponds). Membrane-associated proteins of haloarchaea, such as surface layer (S-layer) proteins, transporters, retinal proteins, and internal organellar membrane proteins including intracellular gas vesicle proteins and those associated with polyhydroxyalkanoate (PHA) granules, contribute greatly to their environmental adaptations. This review focuses on these haloarchaeal cellular and organellar membrane-associated proteins, and provides insight into their physiological significance and biotechnological potential.
嗜盐古菌(haloarchaea)栖息于高盐环境中,能够耐受极端盐度、低氧和营养物质匮乏,并且在某些情况下还能耐受高 pH 值(苏打湖)和辐照(盐田池塘)。嗜盐古菌的膜相关蛋白,如表面层(S-layer)蛋白、转运蛋白、视蛋白和内部细胞器膜蛋白,包括细胞内气泡蛋白和与聚羟基烷酸(PHA)颗粒相关的蛋白,对其环境适应具有重要作用。本综述重点介绍了这些嗜盐古菌的细胞和细胞器膜相关蛋白,并探讨了它们的生理意义和生物技术潜力。