Rastogi S K, Gupta B N, Mathur N, Husain T
Epidemiology Division, Industrial Toxicology Research Centre, Lucknow, India.
Am J Ind Med. 1990;18(6):707-15. doi: 10.1002/ajim.4700180609.
The pulmonary function status of 73 glass bangle workers suffering from chronic bronchitis having varied exposures to pulmonary toxicants in the work environment was evaluated in 1984. The findings were compared with those observed in 220 asymptomatic glass bangle workers and 88 unexposed controls. There was a higher prevalence (45.2%) of ventilatory dysfunction in the chronic bronchitic cases as compared to 19% in the asymptomatic workers and 2.3% in controls, respectively. The relative risk of airway obstruction was 8.3 and 19.6 times higher in the asymptomatic and chronic bronchitic workers respectively as compared to the controls (p less than 0.001). The prevalence of obstructive impairment among the smokers and non-smokers in the exposed workers was not statistically significant. However, age greater than 30 was found to be significantly associated with bronchial obstruction in chronic bronchitic cases. The relative risk of duration of exposure was found to be 1.86 in the asymptomatic workers exposed for more than 10 years (p less than 0.05) while it was 1.62 in workers with chronic bronchitis. The occupational and environmental factors responsible for the high prevalence of chronic bronchitis and associated ventilatory dysfunction in relatively young glass bangle workers are discussed.
1984年，对73名患有慢性支气管炎且在工作环境中接触不同程度肺部毒物的玻璃手镯工人的肺功能状况进行了评估。将这些结果与220名无症状玻璃手镯工人和88名未接触者的结果进行了比较。慢性支气管炎患者的通气功能障碍患病率较高（45.2%），而无症状工人和对照组的患病率分别为19%和2.3%。与对照组相比，无症状工人和慢性支气管炎工人气道阻塞的相对风险分别高8.3倍和19.6倍（p<0.001）。暴露工人中吸烟者和非吸烟者的阻塞性损伤患病率无统计学差异。然而，发现年龄大于30岁与慢性支气管炎患者的支气管阻塞显著相关。在暴露超过10年的无症状工人中，暴露持续时间的相对风险为1.86（p<0.05），而在患有慢性支气管炎的工人中为1.62。本文讨论了相对年轻的玻璃手镯工人中慢性支气管炎和相关通气功能障碍高患病率的职业和环境因素。
