Bellenger C R, Maddison J E, MacPherson G C, Ilkiw J E
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Aust Vet J. 1990 Sep;67(9):317-20. doi: 10.1111/j.1751-0813.1990.tb07813.x.
Ten male and 4 female dogs with chronic hypertrophic pyloric gastropathy were seen at the Sydney Veterinary Teaching Hospital in the period 1982-88. The most commonly affected breeds were the Shihtzu and Maltese. The mean age was 8.2 yr and the mean body weight 6.5 kg. The most common clinical signs were vomiting, weight loss, polydipsia and depression. Hypokalaemia was present in 11 of 12 dogs examined and hypochloraemia in 10 of 11 dogs examined. Five of the six dogs that had blood gases measured were found to have a metabolic alkalosis. Surgery was performed on 13 dogs; pyloromyotomy 7, pyloroplasty 4, gastroduodenostomy 2. There was a recurrence of symptoms in one pyloromyotomy dog, and fatal ulceration and perforation of the cardia occurred in one pyloroplasty case. The remaining 11 dogs had a mean known symptom-free survival time of 20 mo. This study confirms the preponderance of affected males, identifies electrolyte and blood gas disturbances as significant complication of chronic hypertrophic pyloric gastropathy, and suggests that relatively minor surgery (pyloromyotomy) may have a place in the treatment of a selected subgroup of cases.
1982年至1988年期间,悉尼兽医教学医院收治了10只雄性和4只雌性患有慢性肥厚性幽门胃病的犬。最常受影响的犬种是西施犬和马尔济斯犬。平均年龄为8.2岁,平均体重6.5千克。最常见的临床症状是呕吐、体重减轻、多饮和抑郁。12只接受检查的犬中有11只存在低钾血症,11只接受检查的犬中有10只存在低氯血症。6只接受血气测量的犬中有5只被发现患有代谢性碱中毒。13只犬接受了手术;7只进行了幽门肌切开术,4只进行了幽门成形术,2只进行了胃十二指肠吻合术。1只接受幽门肌切开术的犬出现症状复发,1例接受幽门成形术的犬发生贲门致命性溃疡和穿孔。其余11只犬已知的平均无症状生存时间为20个月。本研究证实了患病雄性犬占优势,确定电解质和血气紊乱是慢性肥厚性幽门胃病的重要并发症,并表明相对较小的手术(幽门肌切开术)可能在部分选定病例的治疗中占有一席之地。