Amene C, Yeh-Nayre L A, Dory C E, Crawford J R
Department of Neurosurgery, University of California, San Diego, and Rady Children's Hospital, San Diego, Calif., USA.
Case Rep Neurol. 2012 Jan;4(1):68-70. doi: 10.1159/000338631. Epub 2012 Apr 24.
A 13-year-old girl with a remote history of juvenile pilocytic astrocytoma developed acute onset flushing, tachycardia and shortness of breath immediately following administration of gadopentetate dimeglumine during routine brain MRI that subsided following intravenous diphenhydramine. A retrospective review of the MRI results revealed multiple areas of contrast enhancement of the face, consistent with observed urticaria. The patient received pretreatment medications prior to subsequent gadolinium injections without incident. Gadolinium allergy is extremely rare and has been reported in less than 0.1% of injections. However, in patients who undergo anesthesia for MRI studies, similar subtle extracranial MRI findings should alert the neuroradiologist to possible gadolinium allergy that may warrant premedication prior to future injections.
一名有幼年型毛细胞性星形细胞瘤病史的13岁女孩，在常规脑部MRI检查中静脉注射钆喷酸葡胺后立即出现急性脸红、心动过速和呼吸急促，静脉注射苯海拉明后症状缓解。对MRI结果的回顾性分析显示面部有多个对比增强区域，与观察到的荨麻疹相符。该患者在随后的钆注射前接受了预处理药物，未发生意外。钆过敏极为罕见，报道的发生率低于0.1%。然而，对于接受MRI检查麻醉的患者，类似的轻微颅外MRI表现应提醒神经放射科医生注意可能的钆过敏，这可能需要在未来注射前进行预处理。
