Roje-Bedeković Marina, Vargek-Solter Vesna, Bedek Darko, Demarin Vida
University Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Acta Clin Croat. 2011 Dec;50(4):577-80.
A case is reported of a 72-year-old woman who presented with severe vertigo, vomit, and mild neck and occipital pain. She had a medical history of hypertension, angina pectoris, cholelithiasis, gastric ulcer, pyelonephritis and periodical mild dizziness. Neuroimaging revealed right vertebral artery occlusion, right cerebellar stroke and basilar impression. The therapeutic approach chosen in our patient was conservative, with non-steroid anti-inflammatory drugs and neck collar. Although our patient's prior risk factors for stroke supported a diagnosis of vertebrobasilar stroke, it is possible that the vertebral artery occlusion was the result of changes in the atlantoaxial anatomy and that cerebellar infarction was secondary to craniocervical anomaly. Although the presence of vertebral artery occlusion, cerebellar stroke and basilar impression in our patient may have been coincidental, we suggest that patients with basilar impression and craniocervical anomalies in general may be at an increased risk of vertebrobasilar vascular disease and vertebrobasilar stroke.
报告了一例72岁女性患者,其表现为严重眩晕、呕吐以及轻度颈部和枕部疼痛。她有高血压、心绞痛、胆石症、胃溃疡、肾盂肾炎病史,且有周期性轻度头晕。神经影像学检查显示右椎动脉闭塞、右小脑卒中以及颅底凹陷。我们为该患者选择的治疗方法是保守治疗,使用非甾体类抗炎药并佩戴颈托。尽管我们患者先前的卒中风险因素支持椎基底动脉卒中的诊断,但椎动脉闭塞可能是寰枢椎解剖结构改变的结果,小脑梗死可能继发于颅颈异常。虽然我们患者中椎动脉闭塞、小脑卒中和颅底凹陷的存在可能是巧合,但我们认为一般而言,患有颅底凹陷和颅颈异常的患者可能患椎基底动脉血管疾病和椎基底动脉卒中的风险增加。