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伴有弥漫性冠状动脉微动脉瘤形成的重复性支架骨折——西罗莫司洗脱支架超敏反应?

Repetitive stent fractures with diffuse coronary artery microaneurysm formation--sirolimus eluting stent hypersensitivity?

作者信息

Pavlović Nikola, Stambuk Kresimir, Gabrić Ivo Darko, Trbusić Matias, Krcmar Tomislav, Manola Sime, Pintarić Hrvoje, Radeljić Vjekoslav, Delić-Brkljacić Diana, Vinter Ozren

机构信息

Department of Cardiology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2011 Dec;50(4):609-13.

PMID:22649895
Abstract

While drug eluting stents (DES) are being more widely used in ever more patients receiving DES each day, some new complications may be emerging. Stent fractures and hypersensitivity reactions to stents are among recognized complications that can lead to therapeutic dead end from the interventional cardiologist's point of view. We present a case in which we reached therapeutic dead end with a sirolimus eluting stent, i.e. repetitive stent fractures with diffuse microaneurysms along the implanted DES, possibly due to hypersensitivity reaction to parts of the stent.

摘要

尽管药物洗脱支架(DES)在越来越多的患者中得到更广泛的应用,每天都有更多患者接受DES治疗,但一些新的并发症可能正在出现。支架断裂和对支架的超敏反应是已被认识到的并发症,从介入心脏病学家的角度来看,这些并发症可能导致治疗陷入困境。我们报告一例使用西罗莫司洗脱支架导致治疗陷入困境的病例,即沿植入的DES出现弥漫性微动脉瘤的重复性支架断裂,这可能是由于对支架部分成分的超敏反应所致。

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