[围产期输血的危险因素]

[Risk factors of perinatal blood transfusion].

作者信息

Wang Li, Chen Meng, Zhang Li, Gao Qian, Luo Fang-Yuan, Zhang Li, Liu Xing-Hui

机构信息

Department of Obstetrics and Gynecology, Pengzhou Maternity Child Care Center, Chengdu 611930, China.

出版信息

Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;43(2):214-7.

PMID:22650034

Abstract

OBJECTIVE

To investigate the risk factors associated with perinatal packed red blood cell transfusion.

METHODS

We performed univariable analysis and unconditional multivarible logistic regression analysis to identify risk factors associated with perinatal packed red blood cell transfusion in 19 456 obstetrical inpatients.

RESULTS

The transfusion rate was 1.49% (289/19,456). Prenatal hematocrit (HCT) less than 25% (OR 45.3, 95% CI 27.4-74.9), placenta previa (OR 16.8, 95% CI 11.6-24.3), prenatal HCT 25%-30% (OR 11.4, 95% CI 6.7-19.7), ethnic minority (OR 4.8, 95% CI 1.6-14.0), placenta abruption (OR 4.5, 95% CI 1.7-11.5), multiple gestation (OR 2.8, 95% CI 1.6-4.9) and preeclampsia (OR 2.6, 95% CI 1.5-4.4) were risk factors associated with perinatal packed red blood cell transfusion.

CONCLUSION

Although the overall perinatal transfusion rate is low, severe prenatal anemia (HCT 25%) and placenta previa can increase the risk of transfusion markedly. It is crucial for obstetricians to provide appropriate perinatal care for those patients.

摘要

目的

探讨围产期输注浓缩红细胞的相关危险因素。

方法

我们对19456例产科住院患者进行单因素分析和无条件多变量逻辑回归分析，以确定围产期输注浓缩红细胞的相关危险因素。

结果

输血率为1.49%（289/19456）。产前血细胞比容（HCT）低于25%（比值比45.3，95%可信区间27.4 - 74.9）、前置胎盘（比值比16.8，95%可信区间11.6 - 24.3）、产前HCT为25% - 30%（比值比11.4，95%可信区间6.7 - 19.7）、少数民族（比值比4.8，95%可信区间1.6 - 14.0）、胎盘早剥（比值比4.5，95%可信区间1.7 - 11.5）、多胎妊娠（比值比2.8，95%可信区间1.6 - 4.9）和子痫前期（比值比2.6，95%可信区间1.5 - 4.4）是围产期输注浓缩红细胞的相关危险因素。