Novak Vesna, Stefanović Ivan, Kostić Aleksander, Novak Martin
Srp Arh Celok Lek. 2012 Mar-Apr;140(3-4):138-41. doi: 10.2298/sarh1204138n.
The occurrence of infection after the placement of an extraventricular drainage (EVD) catheter can be a very serious problem in neurosurgery.
The aim of this study was to confirm that the use of special catheters with impregnated antibiotics decreased the percentage of infection.
The prospective study conducted at the Clinic of Neurosurgery in Nis in the period 2006-2009 is presented. Group 1 comprised of 43 patients in whom a commonly used system for EVD was applied. Group 2 comprised of 39 patients in whom the Rifampycin and Clindamycin impregnated EVD catheters were applied (Bactiseal catheters).
In Group 1 infection occurred in nine patients, mainly caused by bacteria of Staphylococcus genus. In Group 2 only two patients developed infections caused by Acinetobacter.
The use of Bactiseal EVD catheters considerably decreased the percentage of infection occurrence with prolonged EVD catheter drainage period.
在神经外科手术中，脑室外引流（EVD）导管置入后发生感染可能是一个非常严重的问题。
本研究的目的是证实使用含抗生素浸渍的特殊导管可降低感染率。
介绍了2006年至2009年期间在尼什神经外科诊所进行的前瞻性研究。第1组由43例应用常用EVD系统的患者组成。第2组由39例应用含利福平与克林霉素的EVD导管（抗菌封套导管）的患者组成。
第1组有9例患者发生感染，主要由葡萄球菌属细菌引起。第2组仅有2例患者发生由不动杆菌引起的感染。
使用抗菌封套EVD导管在延长EVD导管引流期时可显著降低感染发生率。
