Requena L, Sanchez Yus E
Department of Dermatology, University Hospital of San Carlos, Madrid, Spain.
Br J Dermatol. 1990 Dec;123(6):757-63. doi: 10.1111/j.1365-2133.1990.tb04193.x.
We report 22 cases of pigmented spindle cell naevus (PSCN). The usual appearance of these naevi is that of a heavily pigmented papule found mostly on the legs of young patients. Histologically, PSCN was characterized by symmetrical proliferation of spindle-shaped pigmented melanocytes grouped in large junctional nests. Pagetoid spread of single cells in the overlying epidermis was frequently found. In our opinion, PSCN is a distinctive benign acquired melanocytic naevus that in the past has been frequently misdiagnosed as atypical Spitz naevi or malignant melanoma.
我们报告了22例色素性梭形细胞痣(PSCN)。这些痣的常见表现为色素沉着明显的丘疹,多见于年轻患者的腿部。组织学上,PSCN的特征是梭形色素性黑素细胞对称增殖,聚集成大的交界性巢。在上覆表皮中经常发现单个细胞的派杰样播散。我们认为,PSCN是一种独特的良性后天性黑素细胞痣,过去常被误诊为非典型斯皮茨痣或恶性黑色素瘤。