Institute of Environmental Health & Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan.
J Occup Environ Hyg. 2012;9(7):427-36. doi: 10.1080/15459624.2012.685851.
A solid-phase microextraction (SPME) device was used as a diffusive sampler for airborne propylene glycol ethers (PGEs), including propylene glycol monomethyl ether (PGME), propylene glycol monomethyl ether acetate (PGMEA), and dipropylene glycol monomethyl ether (DPGME). Carboxen-polydimethylsiloxane (CAR/PDMS) SPME fiber was selected for this study. A polytetrafluoroethylene (PTFE) tubing was used as the holder, and the SPME fiber assembly was inserted into the tubing as a diffusive sampler. The diffusion path length and area of the sampler were 0.3 cm and 0.00086 cm(2), respectively. The theoretical sampling constants at 30°C and 1 atm for PGME, PGMEA, and DPGME were 1.50 × 10(-2), 1.23 × 10(-2) and 1.14 × 10(-2) cm(3) min(-1), respectively. For evaluations, known concentrations of PGEs around the threshold limit values/time-weighted average with specific relative humidities (10% and 80%) were generated both by the air bag method and the dynamic generation system, while 15, 30, 60, 120, and 240 min were selected as the time periods for vapor exposures. Comparisons of the SPME diffusive sampling method to Occupational Safety and Health Administration (OSHA) organic Method 99 were performed side-by-side in an exposure chamber at 30°C for PGME. A gas chromatography/flame ionization detector (GC/FID) was used for sample analysis. The experimental sampling constants of the sampler at 30°C were (6.93 ± 0.12) × 10(-1), (4.72 ± 0.03) × 10(-1), and (3.29 ± 0.20) × 10(-1) cm(3) min(-1) for PGME, PGMEA, and DPGME, respectively. The adsorption of chemicals on the stainless steel needle of the SPME fiber was suspected to be one of the reasons why significant differences between theoretical and experimental sampling rates were observed. Correlations between the results for PGME from both SPME device and OSHA organic Method 99 were linear (r = 0.9984) and consistent (slope = 0.97 ± 0.03). Face velocity (0-0.18 m/s) also proved to have no effects on the sampler. However, the effects of temperature and humidity have been observed. Therefore, adjustments of experimental sampling constants at different environmental conditions will be necessary.
采用固相微萃取（SPME）装置作为空气中丙烯乙二醇醚（PGEs）的扩散采样器，包括丙二醇单甲醚（PGME）、丙二醇单甲醚乙酸酯（PGMEA）和二丙二醇单甲醚（DPGME）。本研究选用羧基/聚二甲基硅氧烷（CAR/PDMS）SPME 纤维。聚四氟乙烯（PTFE）管用作固定器，将 SPME 纤维组件插入管内作为扩散采样器。采样器的扩散路径长度和面积分别为 0.3cm 和 0.00086cm(2)。在 30°C 和 1 大气压下，PGME、PGMEA 和 DPGME 的理论采样常数分别为 1.50×10(-2)、1.23×10(-2)和 1.14×10(-2)cm(3)min(-1)。为了评估，通过气囊法和动态生成系统，在特定相对湿度（10%和 80%）下产生了接近阈限值/时间加权平均值的已知 PGE 浓度，同时选择了 15、30、60、120 和 240min 作为蒸气暴露时间。在 30°C 下，在暴露室内将 SPME 扩散采样方法与职业安全与健康管理局（OSHA）有机方法 99 进行了平行比较，用于 PGME 的分析采用气相色谱/火焰离子化检测器（GC/FID）。在 30°C 下，采样器的实验采样常数分别为（6.93±0.12）×10(-1)、（4.72±0.03）×10(-1)和（3.29±0.20）×10(-1)cm(3)min(-1)，用于 PGME、PGMEA 和 DPGME。不锈钢针上的化学物质吸附被怀疑是理论和实验采样率之间存在显著差异的原因之一。SPME 装置和 OSHA 有机方法 99 对 PGME 结果之间的相关性呈线性（r=0.9984）且一致（斜率=0.97±0.03）。流速（0-0.18m/s）也被证明对采样器没有影响。然而，已经观察到温度和湿度的影响。因此，在不同的环境条件下，需要对实验采样常数进行调整。
