Leung Wai Sang Stephane, Chaturvedi Rakesh K, Iqbal Sameena, Lachapelle Kevin, de Varennes Benoit
Division of Cardiac Surgery, Royal Victoria Hospital, McGill University Health Center, Montreal, Quebec, Canada.
J Card Surg. 2012 Jul;27(4):408-14. doi: 10.1111/j.1540-8191.2012.01468.x. Epub 2012 May 31.
The aim of this study was to determine the midterm functional quality of life in octogenarians after open valvular surgery.
One hundred and eighty-five consecutive patients above age 80 had valvular surgery with or without coronary artery bypass grafting (CABG). Using the Karnofsky Performance score and Barthel Index, patients were evaluated for functional autonomy, living disposition, and leisure activity by a single telephone interview. Subgroup analysis was performed on the 49 cases of isolated aortic valve replacement (AVR).
Mean age of octogenarians undergoing valvular surgery was 82.7 years (range 80 to 92 years). Actuarial survival at one and three years was 71% and 59%, respectively, for the entire group, compared to 84% and 71%, respectively, for isolated AVRs. After a mean follow-up of 38 months there were 110 survivors (59.5%). Among survivors, 66% were autonomous, 26% semiautonomous, and 8% deemed dependent. Seventy-two percent were living at home, 19% in a residence, and 9% in a supervised nursing facility. Over 90% of patients pursued leisure activities in the social, cognitive, and physical domains.
Valvular surgery in high-risk octogenarians, can be performed with acceptable mortality rates, and provide patients with functional autonomy and an excellent quality of life.
本研究旨在确定高龄患者接受心脏瓣膜开放手术后的中期生活质量功能。
185例连续80岁以上患者接受了瓣膜手术,部分患者还接受了冠状动脉搭桥术(CABG)。通过单次电话访谈,使用卡诺夫斯基性能评分和巴氏指数对患者的功能自主性、生活安排和休闲活动进行评估。对49例单纯主动脉瓣置换术(AVR)患者进行亚组分析。
接受瓣膜手术的高龄患者平均年龄为82.7岁(范围80至92岁)。整个组1年和3年的精算生存率分别为71%和59%,而单纯AVR患者分别为84%和71%。平均随访38个月后,有110名幸存者(59.5%)。在幸存者中,66%为自主生活,26%为半自主生活,8%为依赖生活。72%的患者居家生活,19%居住在养老院,9%在有监督的护理机构。超过90%的患者在社交、认知和身体方面进行休闲活动。
高危高龄患者进行瓣膜手术,死亡率可接受,并能为患者提供功能自主性和优异的生活质量。