Huber Christoph H, Goeber Volkhard, Berdat Pascal, Carrel Thierry, Eckstein Friedrich
Division of Cardiovascular Surgery, University Hospital of Lausanne, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.
Eur J Cardiothorac Surg. 2007 Jun;31(6):1099-105. doi: 10.1016/j.ejcts.2007.01.055. Epub 2007 Mar 19.
Assessment of postoperative quality of life in patients over 80 years after cardiac surgery including coronary artery bypass grafting (CABG), aortic valve replacement (AVR) and combined procedures.
Quality of life of n=136 patients over 80 years at operation (82.3+/-2.1 years), undergoing isolated CABG in 61 patients (45%), isolated AVR in 34 patients (25%) and a combination of CABG and AVR in 41 patients (30%) between January 1999 and December 2003 was reviewed. Preoperatively 66.2% presented in NYHA-class III/IV or CCS-class III/IV. Mean ejection fraction (EF) was 59.5%+/-14.0 (range 25-90%). Quality of life assessment was performed via a Seattle Angina Questionnaire. Follow-up was 100% complete for a total of 890 days (69-1853 days).
Five-year survival was 70% for the CABG group, 75% for the AVR group and 65% for the CABG/AVR group. Quality of life was remarkable in all of the three groups after surgery. Overall 97 patients (81%) were not or little disabled in their daily activity. One hundred and twelve patients (93%) were free or considerably less symptomatic. Seventy-eight patients or 65% reported to be very satisfied with their current quality of life and 112 patients (93%) felt very reassured to have continuous full access to medical treatment despite of their advanced age.
A remarkable quality of life and important improvement in the functional status after cardiac surgery in patients over 80 paired with a satisfactory medium-term survival justify early intervention for heart disease in this age group. Therefore, referral practice for patients over 80 years for heart surgery should be handled liberally.
评估80岁以上患者心脏手术后的生活质量,包括冠状动脉旁路移植术(CABG)、主动脉瓣置换术(AVR)及联合手术。
回顾1999年1月至2003年12月期间136例手术时年龄超过80岁(82.3±2.1岁)的患者的生活质量,其中61例(45%)接受单纯CABG,34例(25%)接受单纯AVR,41例(30%)接受CABG与AVR联合手术。术前66.2%的患者为纽约心脏协会(NYHA)心功能III/IV级或加拿大心血管学会(CCS)心功能III/IV级。平均射血分数(EF)为59.5%±14.0(范围25 - 90%)。通过西雅图心绞痛问卷进行生活质量评估。随访100%完成,共890天(69 - 1853天)。
CABG组的5年生存率为70%,AVR组为75%,CABG/AVR组为65%。术后三组患者的生活质量均显著改善。总体而言,97例(81%)患者日常活动无残疾或残疾轻微。112例(93%)患者无症状或症状明显减轻。78例(65%)患者报告对当前生活质量非常满意,112例(93%)患者尽管年事已高,但仍对能持续获得全面医疗救治感到非常安心。
80岁以上患者心脏手术后生活质量显著提高,功能状态明显改善,中期生存率令人满意,这证明对该年龄组的心脏病进行早期干预是合理的。因此,对于80岁以上患者的心脏手术转诊应放宽处理。